System Biosciences Stratech

SBIisasmallbiotechcompanythat’sdeliveredinnovativeproductsandservicesformolecularandcellBIOLOGyresearchsinceJanuary2004,whentheysoldtheirfirstlentivectorsandpPACKlentiviruspackagingsystems.

Theyfocusonbeingthefirstcompanytobringthemostrecentmethodologiestomarket—theywerethefirstcompanytodeliverexosomeresearchreagentsandCRISPR/Cas9vectors—soresearcherscouldquicklytakeadvantageofthelatest,mostpowerfulapproaches.

Dedicatedtoquality,manyoftheirproductsandmostoftheirserviceofferingsarecompletedintheirstate-of-the-artfacilityinPaloAltoCA,enablingthemtomaintaincontrolovermanufacturingconditionsandquality,ensuretheirserviceprojectsremainconfidentialanddeliverfrequentandtimelyserviceprojectstatusupdates.

TheirexperiencedstaffincludesahighproportionofPhD-levelscientistswhointeractdirectlywithcustomerstoprovideproductandservicessupport.

Supportingallaspectsofyourexosomeresearch,SBI’sproductsenablequantitative,high-throughput,andhighqualitystudiesanddeliverunparalleledcapABIlities

Geteverythingyouneedforstudyingandusingexosomes,fromisolationandcharacterization,tocargoprofilingandengineering,andmore.Whatevermethodsyouchoose—whetheryouuseExoQuickordensitygrADIentultracentrifugation,wantqPCR-basedexosomalmiRNAprofilingorRNA-Seqmethods—we’vegotthehigh-qualityexosomeresearchproductstosupportyourscienceandadvanceyourwork.

Pairingflexibilityandchoicewithexperiencedscientificsupport,ourwiderangeofCRISPR/Cas9productsputthepowerofgenomeengineeringintoyourhands

ReadytouseCRISPR/Cas9?ThenSBI’sreadyforyou.WithacomprehensiveselectionofCRISPR/Cas9productsforgenomeengineering—includingCas9andgRNAdeliverysystemsinaflexIBLerangeofformats,homologousrecombinationdonorvectors,andAAVS1SafeHarbortargeting—wecanbringyourgenomeengineeringprojectstolife.Evenbetter,ourexperiencedtechnicalsupportteamisavailabletoansweryourquestionsonvectordesign,experimentalsetup,andmore—justusetheContactpagetostarttheconversation.

Widelyregardedintheindustryfordeliveringhigh-quality,hightiterlentiviruspreparations,SBI’sLentivirusProductionProductspowercuttingedgeresearchacrossarangeofapplications

Whatevertypeofcellyou’retryingtotransduce,from293TcellstothemoredifficulttypeslikeTcellsandBcells,qualitymatters.WhichiswhySBIoffersoptimizedviruspackagingsystemsandreagentsthatcanhelpyoureliablyobtainhightiterpreparationsandefficienttransfectionandtransduction.

Offeringintegratingandnon-integratingvectorsinviralandnon-viralsystems,SBIoffersawealthofoptionsforgenedeliveryandexpression

Withawealthofoptionsforgenedeliveryandexpression,SBIhasthegeneexpressionvectorstosupportawidevarietyofprojects.Weofferviralandnon-viralsystemsthatcanintegrateintothegenomeorremainepisomalaswellasinduciblesystemsforhighlycontrolledexpression.Notquitesurewhatyouneed?Contactoneofourtechnicalsupportscientists—usetheformontheContactpagetogettheconversationstarted.

Deliveringunparalleledinsightintothecell,SBI’swiderangeofImagingReporterVectorsprovideready-built,ready-to-useconstructsfortoday’sbusylabs

GainclearerinsightintotheinnerworkingsofthecellwithoneormoreofSBI’smanyImagingReporterVectors.Visualizesubcellularcompartmentsandtrackphysiologicalprocessessuchasdifferentiation,signaltransduction,apoptosis,andmorewithourrobust,reliableconstructs.

FromprofilingtooverexpressionforbioMarkerdiscovery,basicandtranslationalresearch,andmore,SBI’sgotthelongandshortofnon-codingRNAcovered

Nomattertheapplication,whetheryou’recheckingindividualmiRNAorlncRNAexpressionlevelsorprofilingarangeofconstructs,knocking-downoroverexpressingmiRNAs,SBI’sgotyourmiRNAresearchandlncRNAresearchtoolscovered.Selectfromawide-rangeofpre-madeexpressionorknockdownconstructs,oruseoneofourexpertlycuratedprofilingarrays.

Forcomprehensive,end-to-endexosomeservicesthatincludeexperttechnicalanddatainterpretationsupportfromahighlyexperiencedteam,youcanrelyonSBI

CRISPR/Cas9Services
SBI’sCRISPR/Cas9Servicescancoverallorjustpartofyourentiregenomeengineeringworkflow

MinicircleServices
GetsustainedtransgeneexpressionfreefromforeignDNA

LentivirusPackaging
Gethigh-titer,transduction-readylentivirusinaslittleastendays

StableCellLines
Getcustomreporter,overexpression,orothertypeofcelllinefastandhassle-free

SimultaneousDetectionofcfDNAandExosomalBiomarkers

ExpandingbiomarkerresearchcapabilitiesAccelerateandenhanceyourbiomarkerdiscoveryandcharacterizationstudieswiththeXCF™COMPLETEExosomecfDNAReadMore

StemCell

FrequentlyAskedQuestions(FAQs)Q:Whatmethodofreprogrammingsourcecellsisthemostefficient?A:TheretroviralmethodofReadMore

MicroRNA

FrequentlyAskedQuestions(FAQs)MicroRNAprofilingQ:HowshouldIprepareorpurifymyRNApriortoQuantiMirCDNAsynthesis?ReadMore

Exoquick

ExoQuickFrequentlyAskedQuestions(FAQs)Q:HowdoIdecidewhichExoQuickproducttostartwith?ExoQuickorExoQuick-TC??A:ReadMore

ExosomesExplainedHowtouseExosomes

ExosomesTools,fromisolationtoengineeringExosomes–extracellularvesicles(EVs)30–200nminsizewereoncethoughtReadMore

HowLentivirusDeliveryWorks

Thepseudoviralparticlescaninfecttargetcellsandexpressgenes,shRNAs,microRNAsandreportermoleculesbutcannotreplicatewithintheReadMore

Exo-Fect™ExosomeTransfection

Exo-Fectisanovelnucleicacidtransferagentthatenablesthetransfectionofnucleicacidsdirectlyintoisolatedexosomes.TheReadMore

PinPointTargetedIntegrationSystem

ThePinPointTargetedIntegrationsystemallowsuserstoeasilyandefficientlycreateisogenicstablecelllinesinmammalianandotherReadMore

MinicircleDNAVectorTechnology

TheMinicircleadvantageMinicirclesareepisomalDNAvectorsthatareproducedascircularexpressioncassettesdevoidofanybacterialplasmidReadMore

PureFection™TransfectionReagent

PureFection™Nanotechnology-basedTransfectionReagentDelivermoreDNAandsiRNAstocellsthantheleadinglipid-basedtransfectionkitsPureFectionisReadMore

ExosomeResearchTools

ComprehensiveToolsetExoQuickIsolationExo-FBSmediaAntibodiesandELISAsExo-RNAPurificationExo-RNANext-GenSequencingWhyareexosomesimportant?OnceReadMore

MicroRNAResearch

EverythingyouneedformicroRNAresearchIntegratedsolutionsformicroRNAanalysisSBIhasdevelopedinnovativetechnologiesandtoolsforReadMore

ColdFusionCloningKit

TheColdFusiontechnologyisasimple,rapidandhighlyefficientcloningkit.ItallowsyoutodirectlycloneanyReadMore

ExosomeAntibodies,ArraysandELISAKitsDetectandquantitateisolatedexosomes

TrackandQuantitateExosomeswithAntibodiesandELISAsExosomesaresmallmembranevesiclessecretedbymostcelltypesinReadMore

SamplePreperation

OverviewGoodsamplepreparationisarguablythemostcriticalstepinanyanalyticalprocessbecausemosttechniquesareunabletoReadMore

AnalysisofPCR

OverviewAnalysingandvisualisingyourresultsisoftentheculminationofweeksifnotmonthsofworkandcanbeReadMore

GeneticEngineeringMastertheEssentials

OverviewInMolecularBiology,theabilitytosuccessfullymanipulateDNAisessential. Stratechofferscuttingedgecloningsystems,genomeeditingReadMore

Visualisation

OverviewTherearemanywaysofvisualisingyourresults;someofthemmorevisualthanothers!StratechsupplysensitiveReadMore

phiC31IntegraseVectorSystemOne-stepGeneAdditionTechnology

NEWfromSystemBiosciences(SBI)thephiC31IntegraseCloningsystemformammaliangenomeengineeringapplications.ThissystemprovidestheresearcherReadMore

ExoQuicktheExosomePrecipitationReagent

Exosomesare60–150nmmembranevesiclessecretedbymostcelltypesinvivoandinvitro.ExosomesareReadMore

DELIVERY

weofferfreedeliverytoUKuniversitiesandnonprofitorganisations