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MedKoo Biosciences/ABT767/205762/10mg
ABT-767isanorallyavailableinhibitorofthenuclearenzymespoly(ADP-ribose)polymerase(PARP)1and2,withpotentialantineoplasticactivity.Uponadministration,ABT-767selectivelybindstoPARP1and2,therebypreventingrepairofdamagedDNAviathebaseexcisionrepair(BER)pathway.ThisagentenhancestheaccumulationofDNAstrandbreaksandpromotesgenomicinstabilityeventuallyleadingtoapoptosis.ABT-767mayenhancethecytotoxicityofDNA-damagingagentsandreversetumorcellchemo-andradioresistance.

MedKooCat#:205762
Name:ABT-767
CAS#:NONE
ChemicalFormula:
ExactMass:
MolecularWeight:
ElementalAnalysis:


Synonym:ABT767;ABT767;ABT-767

IUPAC/ChemicalName:NONE


TechnicalData

Appearance:
Solidpowder

Purity:
>98%(orrefertotheCertificateofAnalysis)

ShippingCondition:
Shippedunderambienttemperatureasnon-hazardouschemical.ThisproductisstableenoughforafewweeksduringordinaryshippingandtimespentinCustoms.

StorageCondition:
Dry,darkandat0-4Cforshortterm(daystoweeks)or-20Cforlongterm(monthstoyears).

Solubility:
SolubleinDMSO,notinwater

ShelfLife:
>2yearsifstoredproperly

DrugFormulation:
ThisdrugmaybeformulatedinDMSO

StockSolutionStorage:
0-4Cforshortterm(daystoweeks),or-20Cforlongterm(months).

HarmonizedSystemCode:
293490


AdditionalInformation

  
 
 
 


References

 


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