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BioXcell/InVivoMAb anti-mouse LPAM-1 (Integrin α4β7)/DISCOUNTED ACADEMIC OR NON PROFIT: 25MG/BE0034-A025mg

About InVivoMAb anti-mouse Notch4

The HMN4-14 monoclonal antibody reacts with mouse neurogenic locus notch homolog 4 (Notch4) a member of the Notch family of type 1 transmembrane proteins. The Notch signaling pathway is a highly conserved intercellular signaling pathway. Five Notch ligands have been identified including DLL4 and Jagged2. Upon ligand binding the Notch receptor undergoes proteolysis and translocates to the nucleus ultimately activating transcription. The Notch pathway has been shown to play a role in myeloid cell proliferation, hematopoiesis, and embryonic endothelial development.

InVivoMAb anti-mouse Notch4 Specifications

Isotype

Armenian Hamster IgG, κ

Recommended Isotype Control(s)InVivoMAbpolyclonal Armenian hamster IgG(BE0091)
Recommended InVivoPure Dilution BufferInVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

Notch4-Fc recombinant protein

Reported Applications
  • in vitro Notch4 stimulation
  • Flow cytometry
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.

RRID

AB_10948996

Molecular Weight

150 kDa

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