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BioXcell/InVivoMAb anti-mouse TIM-3 (CD366)/DISCOUNTED ACADEMIC OR NON PROFIT 1MG/BE0115-A001mg

AboutInVivoMAbanti-mouseIL-2

TheS4B6-1monoclonalantibodyreactswithmouseIL-2,a17kDacytokinethatismainlyproducedbyTcellsinresponsetoantigenicormitogenicstimulation.IL-2isrequiredforTcellproliferationandotheractivitiescrucialtotheregulationofimmunity.ThecytokinecanalsostimulatethegrowthanddifferentiationofBcells,monocytes/macrophages,andNKcells.Additionally,IL-2preventsautoimmunediseasesbypromotingthedifferentiationofcertainimmatureTcellsintoregulatoryTcells.TheS4B6-1antibodyhasbeenshowntoneutralizeIL-2invivo.

InVivoMAbanti-mouseIL-2Specifications

Isotype

RatIgG2a

RecommendedIsotypeControl(s)InVivoMAbratIgG2aisotypecontrol,anti-trinitrophenol(BE0089)
RecommendedInVivoPureDilutionBufferInVivoPurepH6.5DilutionBuffer(IP0065)
Immunogen

RecombinantmouseIL-2

ReportedApplications
  • invivoIL-2neutralization
  • invivoIL-2receptorstimulation(asacomplexwithIL-2)
Endotoxin
  • <2EU/mg(<0.002EU/μg)
  • DeterminedbyLALgelclottingassay
Purity
  • >95%
  • DeterminedbySDS-PAGE
Formulation
  • PBS,pH6.5
  • ContainsnostABIlizersorpreservatives
Sterility

0.2μMfiltered

Production

Purifiedfromtissueculturesupernatantinananimalfreefacility

Purification

ProteinG

Storage

Theantibodysolutionshouldbestoredatthestockconcentrationat4°C.Donotfreeze.

MolecularWeight

150kDa

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