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BioXcell/InVivoMAb anti-mouse CD29/REGULAR: 5MG/BE0232-R005mg

AboutInVivoMAbanti-mouseIL-18

TheYIGIF74-1G7monoclonalantibodyreactswithmouseIL-18,an18kDapro-inflammatorycytokine.IL-18isexpressedbyactivatedmacrophages,keratinocytes,Kupffercells,intestinalepithelialcells,andosteoblasts.IL-18hasbeenshowntoactivateNF-κB,induceFasligandexpression,inducebothCCandCXCchemokineexpression,andenhancetheproductionofIFNγandGM-CSF.

InVivoMAbanti-mouseIL-18Specifications

Isotype

RatIgG2a,κ

RecommendedIsotypeControl(s)InVivoMAbratIgG2aisotypecontrol,anti-trinitrophenol(BE0089)
RecommendedInVivoPureDilutionBufferInVivoPurepH7.0DilutionBuffer(IP0070)
Immunogen

Notavailableorunknown

ReportedApplications

invivoIL-18neutralization

Endotoxin
  • <2EU/mg(<0.002EU/μg)
  • DeterminedbyLALgelclottingassay
Purity
  • >95%
  • DeterminedbySDS-PAGE
Formulation
  • PBS,pH7.0
  • ContainsnostABIlizersorpreservatives
Sterility

0.2μMfiltered

Production

Purifiedfromtissueculturesupernatantinananimalfreefacility

Purification

ProteinG

Storage

Theantibodysolutionshouldbestoredatthestockconcentrationat4°C.Donotfreeze.

RRID

AB_2687719

MolecularWeight

150kDa

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