The mAb35 (TIB-175) antibody reacts with human rat and fish acetylcholine receptor (AChR). The AChR is a heterodimeric receptor consisting of four subunits in a molar stoichiometry α2βγδ during the early embryonic stages or after denervation and α2βεδ in the adult form. The mAB35 antibody binds to the major immunogenic region of the α subunits. It has been shown to passively transfer experimental autoimmune myasthenia gravis.
Isotype | Rat IgG1 |
Recommended Isotype Control(s) | InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase(BE0088) |
Recommended InVivoPure Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer(IP0070) |
Immunogen | Electrophorus electricus acetylcholine receptor |
Reported Applications |
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Endotoxin |
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Purity |
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Formulation |
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Sterility | 0.2 μM filtered |
Production | Purified from tissue culture supernatant in an animal free facility |
Purification | Protein G |
Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
RRID | AB_10950153 |
Molecular Weight | 150 kDa |
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