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BioXcell/InVivoMAb anti-mouse CD4/DISCOUNTED ACADEMIC OR NON PROFIT 25MG/BE0003-1-A025mg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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BioXcell/InVivoMAb anti-mouse CD4/DISCOUNTED ACADEMIC OR NON PROFIT 25MG/BE0003-1-A025mg

About InVivoMAb anti-mouse CD4

The GK1.5 monoclonal antibody reacts with the mouse CD4. The CD4 antigen is a 55 kDa cell surface type I membrane glycoprotein belonging to the immunoglobulin superfamily. CD4 acts as a co-receptor which in cooperation with the T cell receptor (TCR) interacts with class II MHC molecules displayed by antigen presenting cells (APC). CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally. The GK1.5 antibody has been shown to compete with clones YTS 177 and YTS 191 for CD4 binding.

InVivoMAb anti-mouse CD4 Specifications

Isotype

Rat IgG2b, κ

Recommended Isotype Control(s)InVivoMAb rat IgG2b isotype control, anti-keyhole limpet hemocyanin(BE0090)
Recommended InVivoPure Dilution BufferInVivoPure pH 6.5 Dilution Buffer(IP0065)
Immunogen

Mouse CTL clone V4

Reported Applications
  • in vivo CD4+ T cell depletion
  • Flow cytometry
  • Western blot
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 6.5
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.

RRID

AB_1107636

Molecular Weight

150 kDa

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