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rPeptide/GammaSynuclein/S10071/0.5 mg
Sequence
MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGAKTKENVVQSVTSVAEKTKEQANAVSEAVVSSVNTVATKTVEEAENIAVTSGVVRKEDLRPSAPQQEGEASKEKEEVAEEAQSGGD
Source
Recombinant.ADNAsequenceencodingthehumangamma-synucleinsequencewasexpressedinE.coli.
Description
Gamma-Synuclein(originallyknownasabreastcancerspecificgeneproduct,BCSG1)isanacidicneuronalproteinof127aminoacids.Itisup-regulatedinthemajorityoflate-stagebreastandovariancancers.Gamma-synucleinmaybeapotentialMarkerforbothlatestagebreastandovariancancers.Morerecently,ithasbeenshownthatgamma-synucleinpromotescancercellsurvivalandinhibitsstress-andchemotherapydrug-inducedapoptosisbymodulatingMAPkinasepathways.
MolecularMass
13,300Da
Purity
>95%bySDS-PAGEandMassSpec.

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