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Sicgen Antibodies/E-Cadherin Polyclonal Antibody/400 µg/AB0057-200

CatalogNo.:AB0057-200

Price/Unit:EUR300.00

Source:Goat

Quantity/unitsize:400µg

Description:GoatpolyclonaltoCDH1.CDH1isaclassicalmemberofthecadherinsuperfamily.Thisproteinisacalciumdependentcell-celladhesionglycoproteincomprisedconsistsof5cadherinrepeatsintheextracellulardomain,onetransmembranedomain,andaandahighlyconservedintracellulardomainthatbindsb-cateninandp120-catenin.CDH1isinvolvedinmechanismsregulatingproliferation,mobilityandcell-celladhesionsofepithelialcells.LossofE-cadherinfunctionorexpressionhasbeenimplicatedincancermetastasisandprogression.Alternativenames:ARC-1,CAM120/80,CD324,CDH1,cdhc-A,CDHE,ECAD,E-CadE-cadherin,Epithelialcadherin,l-cam,LCAM,P09803,P12830/Q9R0T4,UVO,Uvomorulin,XBcad,XB-cadherin,XTCAD-1antibody.

Form:Polyclonalantibodysuppliedasa200µl(2mg/ml)aliquotinPBS,20%glyceroland0.05%sodiumazide.Thisantibodyisepitope-affinitypurifiedfromgoatantiserum.

Immunogen:Recombinantpeptidederivedfromwithinresidues750to850ofhumanCDH1producedinE.coli.

Specificity:DetectsendogenouslevelsoftotalE-cadherinproteinbyWesternblotinthewholecelllysates(COS-7andMDCK).

Reactivity:Reactsagainsthuman,rat,mouse,canineandmonkeyproteins.

Usage:Westernblot                      1:500-1:2,000Immunofluorescence                               NDImmunohistochemistry(paraffin)              NDImmunohistochemistry(frozen)               ND

Reactivitychart

SampleWesternBlotImmuno-fluorescenceImmuno-Histochemistry(p)Immuno-Histochemistry(f)
human+++NDNDND
mouse+++NDNDND
rat+++NDNDND
monkey+++NDNDND
canine+++NDNDND

Storage:Storeat-20Cforlong-termstorage.Storeat2-8Cforuptoonemonth.

Specialinstructions:Avoidfreeze/thawcycles.

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