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CatalogNo.:AB0043-200
Price/Unit:EUR320.00
Source:Goat
Quantity/unitsize:600µg
Description:GoatpolyclonalantibodytoCathepsinD.CathepsinDisalysosomalasparticproteaseofthepepsinfamily.Acidproteaseactiveinintracellularproteinbreakdown.Itiscomposedofadimerofdisulfide-linkedheavyandlightchains,bothproducedfromasingleproteinprecursor.ItisinvolvedinthepathogenesisofseveraldiseasessuchasbreastcancerandpossIBLyAlzheimerdisease.Alternativenames:ceroid-lipofuscinosis,CLN10;CPSD,CTSD,lysosomalaspartylprotease,lysosomalaspartylpeptidase,neuronal10antibody.
Form:Polyclonalantibodysuppliedasa200µl(3mg/ml)aliquotinPBS,20%glyceroland0.05%sodiumazide.Thisantibodyisepitope-affinitypurifiedfromgoatantiserum.
Immunogen:Purifiedrecombinantpeptidederivedfromwithinresidues275aatotheC-terminusofhumanCathepsinDproducedinE.coli.
Specificity:Thisantibodygivesapositivesignalinthefollowinghuman(Jurkat,HT1080,HUH,MDA-MB-231,ARPE19,SH-SY5Y),canine(MDCK)andmonkey(COS-7)wholecelllysates.
Reactivity:Reactsagainsthuman,rat,mouse,canineandmonkeyproteins.
Usage:Westernblot 1:250-1:1,000Immunofluorescence 1:50-1:200Immunohistochemistry(paraffin) 1:50-1:200Immunohistochemistry(frozen) 1:50-1:200IEM 1:50-1:200
Reactivitychart
| Sample | WesternBlot | Immuno-fluorescence | Immuno-Histochemistry(p) | Immuno-Histochemistry(f) | human | +++ | +++ | +++ | +++ | rat | +++ | +++ | +++ | +++ | mouse | +++ | +++ | +++ | +++ | canine | +++ | +++ | +++ | +++ | monkey | +++ | +++ | +++ | +++ |
|---|
Storage:Storeat-20Cforlongtermstorage.Storeat2-8Cforuptoonemonth.
Specialinstructions:Avoidfreeze/thawcycles.
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