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| Synonyms | MonoclonalBTG1antibody,Anti-BTG1antibody,BTG1,BTG1antibody,BTG1,BTG-1,BTG-1antibody,B-celltranslocationgene1antibody |
|---|---|
| Specificity | HumanBTG1 |
| CrossReactivity | Human.Otherspeciesnotstudied |
| Applications | DotBlot |
| Immunogen | BTG1antibodywasraisedinmouseusingrecombinantHumanB-CellTranslocationGene1,Anti-Proliferative(Btg1) |
| Host | Mouse |
|---|---|
| Clone | 2095C1a |
| Isotype | IgG1 |
| MethodofPurification | BTG1antibodywaspurifiedusingproteinGcolumnchromatographyfromculturesupernatantofhybridomaculturedinamediumcontainingbovineIgG-depleted(approximately95%)fetalbovineserum. |
| Form&Buffer | BTG1antibodyinPBS(3.0mMKCl,1.5mMKH2PO4,140mMNaCl,8.0mMNa2HPO4(pH7.4))containing1%bovineserumalbumin(BSA)and0.05%sodiumazide(NaN3). |
| Concentration | 100ug/ml |
| Storage | Storeat2-8degCforuptooneyear.Werecommendlongtermstorageat-20degC.Avoidrepeatedfreezingandthawing. |
|---|---|
| BiohazardInformation | Thisantibodysolutioncontainssodiumazide(NaN)asapreservative.ThereisapotentialhazardthatNaNreactswithcopperorleadtoproduceanexplosivecompound.Forsafedisposal,thevialhastobewashedthoroughlywithwater.Itisstronglyadv |
| UsageRecommendations | Tobeoptimizedbytheenduser. |
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| BiologicalSignificance | Thisgeneisamemberofananti-proliferativegenefamilythatregulatescellgrowthanddifferentiation.ExpressionofthisgeneishighestintheG0/G1phasesofthecellcycleanddownregulatedwhencellsprogressedthroughG1.Theencodedproteininteractswithseveralnuclearreceptors,andfunctionsasacoactivatorofcelldifferentiation.ThislocushasbeenshowntobeinvolvedinachromosomaltranslocationinacaseofB-cellchroniclymphocyticleukemia. |
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