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| ProductName | Cat# | Clone# | Isotype | Applications | Reactivity | Unit/Size |
| AntiHumanDAX1 | PP-H7431-00 | H7431 | IgG2a | EL,WB | Hu | 100ug/0.1ml |
*Description
DSS-AHCcriticalregionontheXchromosome,gene1(DAX1,AHCH;NR0B1)isamemberoforphannuclearreceptor.DAX1isexpressedinadrenalcortex,ovariangranulosa,thecacells,testicularLeydigcells,Sertolicells,anteriorpituitarygonadotropecellsandtheneuronsoftheventromedialnucleusofthehypothalamus.DAX1involvesincontrollingdevelopmentofthehypothalamic-pituitaryaxis,aswellasingonadaldevelopmentandsexdetermination.DAX1wasshowntointeractphysicallywithSF-1.
SpecSheetPP-H7431-00(PDFFile)
| Alias | DAX1,OrphannuclearreceptorDAX-1 |
| GeNEBank | S74720 |
| Nomenclature | NR0B1 |
| Origin | ProducedinBALB/cmouseascitesafterinoculationwithhybridomaofmousemyelomacells(NS-1)andspleencellsderivedfromaBALB/cmouseimmunizedwithBaculovirus-expressedrecombinanthumanDAX1(1-80aa). |
| Specificity | ThisantibodyspecificallyrecognizeshumanDAX1.Notyettestedinotherspecies. |
| Purification | Ammoniumsulfatefractionation |
| Formulation | Physiologicalsalinewith0.1%NaN3asapreservative. |
| Storage | Storeat2C-8Cuptoonemonth.Forlong-termstorage,thesolutionmaybefrozeninworkingaliquots.Repeatedfreezingandthawingisnotrecommended.Storageinafrost-freefreezerisnotrecommended. |
| Reference | |
| Note | Sodiumazidemayreactwithleadandcopperplumbingtoformexplosivemetalazides.FlushwithlargeamountsFormulationofwaterduringdisposal. |
Cautionmustbetakentoavoidcontactwithskinoreyes.Insuchacase,rinsethoroughlyatoncewithwater.Donotingest,inhale,orswallow.Seekmedicalattentionimmediately.Wearappropriateprotectiveclothingsuchaslaboratoryoveralls,safetyglassesandgloves.Itisstronglyadvisedthatthisproductshouldbehandledbypeoplewhohavebeenwelltrainedinlaboratorytechniquesandthatitishandledwithcarepursuanttotheprinciplesofgoodlaboratorypractice.Allchemicalsaredeemedpotentiallyharmful.Thevialispronetofallover.Usecaution,especiallywhenthelidisoff.
FORRESEARCHUSEONLY,NOTFORUSEINDIAGNOSTICPROCEDURES.
*Remark-Icon:
EL=ELISA,WB=WesternBlotting,NW=Non-reducingWesternBlotting,S=SuperShiftAssay.IP=Immunoprecipitation,IHC=Immunohistochemistory,CH=ChIPAssay
Hu=Human,Mo=Mouse,Ra=Rat
Manufacturedby:PerseusProteomics,Inc.
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