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Anaspec/Fluorescein - 5 - maleimide/25 mg/AS-81405

Description
Product NameFluorescein - 5 - maleimide
CAS75350-46-8
Size25 mg
Catalog #AS-81405
US$$167
Purity≥95% by HPLC

Maleimides are among the most frequently used reagents for thiol modification.In most proteins, the site of reaction is at cysteine residues that either are intrinsically present or result from reduction of cystines. Unlike iodoacetamides, maleimides do not react with histidines and methionines under physiological conditions. Fluorescein-5-maleimide is one of the most popular fluorescent dyes for thiol modifications of proteins.

Detailed InformationDatasheet
Material Safety Data Sheets (MSDS)
Storage-20°C desiccated and protected from light
References1. Winograd E, et al. Mol Biochem Parasitol 136, 243-8; (2004).
2. Van der Sluis EO, et al. FEBS Lett 527, 159-65; (2002).
Molecular Weight427.36
Molecular FormulaC24H13 NO7
Spectral PropertiesAbs/Em = 493/515 nm
Solvent SystemDMF or DMSO
Product CitationsNewbern, J. et al. (2007). c-Jun N-terminal kinase signaling regulates events associated with both health and degeneration in motoneurons. Neurosci 147, 680.Kamaduri, H, er al. (2013). Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3. elife2, e00828. doi: 10.7554/eLife.00828.Newbern, J. et al. (2007). c-Jun N-terminal kinase signaling regulates events associated with both health and degeneration in motoneurons. Neurosci 147, 680.
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