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Bachem/FSL-1-FLAG trifluoroacetate salt/H-7926.0500/0.5 mg

Details
ThelipopeptideFSL-1,synthesizedonthebasisoftheN-terminalstructureofaM.salivariumlipoprotein,iscapableofinducingthecellsurfaceexpressionofICAM-1inhumangingivalfibroblasts.ItfurThermorerevealedanactivitytoinduceproductionofmonocytechemoattractantprotein1,interleukin-6(IL-6),andIL-8.FSL-1alsoactivatedmacrophagestoproducetumornecrosisfactoralpha.Overall,resultsbyOkusawaandcoworkerssuggestthatthediacylglycerylandthepeptideportionsofFSL-1areindispensablefortheexpressionofBIOLOGicalactivitiesandfortherecognitionbyToll-likereceptors2and6.Furthermore,thesameauthorsconcludethattherecognitionofFSL-1byToll-likereceptors2and6apparentlyishydrophobic.
ItemNumber4099727
OneLetterCodePam₂CGDPKHPKSFDYKDDDDK
SynonymsFibroblastStimulatingLipopeptide1FLAG-tag
MolecularFormulaC₁₂₅H₁₉₈N₂₄O₃₇S
RelativeMolecularMass2661.15
SourceSynthetic
StorageConditions-20±5°C
AreasofInterestImmunomodulatingAgents
Links/Documents:
  • PeptideCalculator
  • MSDS
Brochures:
Nobrochuresfound.
Productcitations
T.Okusawa,Infect.Immun.,72,1657(2004)
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