CF™dyeAnnexinVconjugateisAnnexinVlabeledwithoursuperiornear-IRfluorescentdye.AnnexinVisa35-36kDaproteinthathasahighaffinityforphosphatidylserine(PS).Innormalviablecells,PSislocatedonthecytoplasmicsurfaceofthecellmembrane.Inapoptoticcells,however,PSistranslocatedfromtheinnertotheouterleafletoftheplasmicmembrane,makingitselfavailableforAnnexinVbinding.
Near-IRfluorescentdyesavailableforthisproductare:CF750,CF680,CF770,CF790andCF800.
TheseCF™dyesarefarmorephotostableandbrighterthanothersimilarnear-IRdyes,suchasAlexaFluor®750,Cy®7andIRDye®800(downloadthe Near-IRDyeFlyerformoreinformation).CF™dyeAnnexinVdoesnotcontainazideorotherpotentiallytoxicmaterials,andthusissuitableforinvivoimaging.
Formoreinformation,downloadourApoptosis,NecrosisandCellViABIlityAssaysBrochure,CF™DyeSelectionGuide,andFlowCytometryProductsBrochure.
DownloadalistofCFdyereferences.
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