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| Product name | C4 ProteinPurified human complement component C4 |
| Cat-Nr. | A402 |
| Intended use | C4 is one of the proteins unique to the Classical Complement Pathway. The 200 kD C4 protein is made up of three peptide chains linked by disulfide bonds and contains a thioesterbond. When the classical pathway is activated, C1s cleaves C4 to C4a (a weak anaphylatoxin) and C4b. C4b can then bind covalently to a target surface or complex. It can then function as an opsonin or participate as part classical pathway convertase. C4 has been shown to exist as two separate "complotypes " C4A and C4B. These have been shown to have different biological properties. Specifications:Concentration: 1.0 mg/mlVolume/Vial: 250 µl/vialStorage: at or below -70°CPurity: > 95%Buffer: PBS Functional Testing:All Quidel complement components are tested for functional activity in a standard lytic or applicable functional assay and for biochemical purity by SDS- polyacrylamide gel electrophoresis. Please refer to the Certificate of Analysis for lot specific information on functional titer. Applications:Quidel"s purified human complement components are useful in a wide variety of immunochemical and research applications. References:
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