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| Product name | Factor BPurified human complement Factor B |
| Cat-Nr. | A408 |
| Intended use | Factor B is one of the proteins unique to the Alternative Complement Pathway. The 93 kD Factor B protein is made up of a single peptide chain. When the alternative pathway is activated either directly or by the classical pathway via the amplification loop, C3b can bind whole Factor B. Factor D can then cleave Factor B in a single site to yield Ba and Bb. Bb can then become the enzymatically active constituent of the C3 and C5 alternative pathway convertases. Specifications:Concentration: 1.0 mg/mlVolume/Vial: 250 µl/vialStorage: at or below -70°CPurity: > 95%Buffer: PBS Functional Testing:All Quidel complement components are tested for functional activity in a standard lytic or applicable functional assay and for biochemical purity by SDS- polyacrylamide gel electrophoresis. Please refer to the Certificate of Analysis for lot specific information on functional titer. Applications:Quidel"s purified human complement components are useful in a wide variety of immunochemical and research applications. References:
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