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Abnova/A2M polyclonal antibody/1kit/PAB28545

  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against recombinant A2M.
  • Immunogen:
  • Recombinant protein corresponding to amino acids of recombinant A2M.
  • Sequence:
  • SVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDDEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEEPHTETVRKYFPETWIWDLVVVNS
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry(1:200-1:500)Western Blot(-)The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Datasheet:
  • PDF DownloadDownload
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: A-431, Lane 4: Liver, Lane 5: Tonsil with A2M polyclonal antibody (PAB28545).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of human liver with A2M polyclonal antibody (Cat # PAB28545) shows moderate cytoplasmic positivity in hepatocytes.
  • Application Image
  • Western Blot
  • Western Blot
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 2
  • Protein Accession#:
  • P01023
  • Gene Name:
  • A2M
  • Gene Alias:
  • CPAMD5,DKFZp779B086,FWP007,S863-7
  • Gene Description:
  • alpha-2-macroglobulin
  • Omim ID:
  • 103950, 104300
  • Gene Ontology:
  • Hyperlink
  • Gene Summary:
  • Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq
  • Other Designations:
  • -
  • Interactome
  • Interactome
  • Gene Pathway
  • Complement and coagulation cascades
  • Related Disease
  • Alzheimer Disease
  • Alzheimer disease
  • Amyloidosis
  • Arthritis, Rheumatoid
  • Cardiovascular Diseases
  • Cognition Disorders
  • Dementia
  • Diabetes Complications
  • Diabetes Mellitus, Type 2
  • Disease Progression
  • Diseases in Twins
  • Edema
  • Essential Tremor
  • Essential tremor
  • Genetic Predisposition to Disease
  • Hepatitis C, Chronic
  • Kidney Failure, Chronic
  • Liver Cirrhosis
  • Macular Degeneration
    • ... see more
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