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Abnova/AFP monoclonal antibody, clone MBS-12/1kit/MAB14250

  • Specification
  • Gene Info
  • Disease
  • Related Products
  • List All
  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant human AFP.
  • Immunogen:
  • Recombinant protein corresponding to full length human AFP.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 70
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)Immunofluorescence (0.5-1 ug/mL)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS.
  • Storage Instruction:
  • Store at -20 to -80°C.Aliquot to avoid repeated freezing and thawing.
  • Datasheet:
  • PDF DownloadDownload
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human fetal liver with AFP monoclonal antibody, clone MBS-12 (Cat # MAB14250).
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 174
  • Protein Accession#:
  • P02771
  • Gene Name:
  • AFP
  • Gene Alias:
  • FETA,HPAFP
  • Gene Description:
  • alpha-fetoprotein
  • Omim ID:
  • 104150
  • Gene Ontology:
  • Hyperlink
  • Gene Summary:
  • This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000160480,alpha-1-fetoprotein,alpha-fetoglobulin
  • Related Disease
  • Carcinoma, Hepatocellular
  • Liver Cirrhosis
  • Liver Neoplasms
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