Axon 5008
CAS [N.A.]
MF #N/AMW #N/A
A convenient set of two small molecule inhiitors, DNA methyltransferase (DNMT) inhibitor RG 108 (Axon 1691) and HMTase inhibitor BIX 01294 trihydrochloride (Axon 1692) (termed RG-BIX or RG/BIX). Combination of BIX 01294 and RG108 was reported to enhance the efficiency of induced pluripotent stem cell (iPS) generation.
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Y. Shi et al. A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell. 2008, 2(6), 525-528. |
T.V. Ho et al. in "Tissue Engineering in Regenerative Medicine. Stem Cell Biology and Regenerative Medicine". 2011. H.S. Bernstein (Ed.). ISBN 978-1-61779-321-9. Chapter 3: Current Status of Induced Pluripotent Stem Cells.2011, 39-52. |
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