Hydrocortisone

英文名Hydrocortisone 
中文名:可的索;皮质醇;氢化皮质酮;氢可的松,氢化可的松 
说明:类别肾上腺皮质激素及促肾上腺皮质激素药 
Sigma相关产品资料：
SigmaH0888 Hydrocortisone
cellculturetested
Synonym:11β,17α,21-Trihydroxypregn-4-ene-3,20-dione,17-Hydroxycorticosterone,4-Pregnene-11β,17α,21-triol-3,20-dione,Cortisol,Kendall’scompoundF,Reichstein’ssubstanceM
CASNumber:50-23-7
LinearFormula:C21H30O5
MolecularWeight:362.46
BeilsteinRegistryNumber:1354819
ECNumber:200-020-1
MDLnumber:MFCD00011654
PubChemSubstanceID:24895415 
Description
ReconstitutionToprepare50μg/mLstocksolution,add1.0mLabsoluteethanolto1.0mgofproduct,gentlyswirltodissolve,add19mLsterilemedium.
Physicalformpowder-RT;stock-frozeninworkingaliquots,avoidrepeatedfreeze/thaw
Biochem/physiolActionsPrimaryglucocorticoidsecretedbytheadrenalcortex.Ithasthreetimestheanti-inflammatorypotencyofcorticosterone butmuchlowerNa2+retentionpotency.
性质
assay≥98%
potency0.004-5μg/mL
mp211-214°C(lit.)
suitABIlitycellculturetested
GeneInformationhuman...ABCB1(5243),CYP3A4(1576),SERPINA6(866)
 rat...Ar(24208),Nr3c1(24413)
 mouse...Abcb1a(18671),Abcb1b(18669),Ifng(15978),Nos2(18126)