Zenbio/Human Serum & AnimalFree Growth Supplement/SERHPL/100ml

ZenBioisproudtoofferseveralnon-animalreplacementsforFetalBovineSerum(FBS):HumanPlateletLysate-(New!),GroProready-to-usegrowthsupplementandHumanABSerum.

ZenBio,Inc.IntroducesGroPro™CellCultureGrowthSupplement
FormulatedtoReplaceBovineSerumAllowingforCulturingof
PrimaryCellsandCellLines

OurNEW!HumanPlateletLysate(HPL)andGroProareanon-animalderivedcellculturegrowthsupplementsobtainedfromhumanplatelets.HPLcontainsabundantgrowthfactorsandcytokinesnecessaryforcellgrowthandproliferation.PlateletlysatecanbeusedasareplacementfortraditionalFetalBovine(FBS)supplementedcellculturemedium.Replacingfetalbovineserum(FBS)withHPLallowsforexpansionandpotentialclinicalgradeproductionoffunctionalmesenchymalstromalcellsbyremovingtheriskofxenogeneicimmunereactionsandtransmissionofbovineprionandviralpathogens.Additionally,HPLandGroProarederivedfromarenewablesourcethatisnottiedtotheanimalslaughterindustryandthepricedoesnotfluctuate!

TheUSFDAismovingtowardsadoptingEuropeanguidelinesrequiringthatbovinematerialsberemovedfromculturingmediaforanytherapeuticproductcontainingculturedcells,thusmakingHPLanattractivealternativetotheR&Dandproduction/manufacturingprocesses.AlllotsarefullytestedforpathogensaccordingtoFDAguidelines.

• 10XmorepotentthanFBS
• StablePricing
• Non-AnimalDerived
• Traceability
• FreeofMycoplasma
• Lot-to-LotConsistency
• SterileCollection
• PoolProcessing
• QCTestedinZenBiosCellProductionSystem

HumanABSerum:

Humanserumoffersatechnicaladvantageoveranimalserumwhenculturingavarietyofhumancelltypes,especiallythosecellsmakinguptheimmunesystem.Thisisalsotheserumofchoicewhendevelopingtissueengineeredandregenerativemedicineproducts,asmanyregulatoryagenciesinagrowingnumberofcountriesarerestrictingtheuseofanimalserumduringthemanufacturingprocess.

SincehumanserumfromtypeABdonorsislackinginantibodiestowardstheAandBblood-typeantigens,thisisthetypemostcommonlyusedasimmunoreactivityisminimizedagainstthehumancellsinculture.Maledonorserumispreferredoverfemale,asthislowerstheriskofmajorhistocompatibilityclass(MHC)antibodiesbeingpresent.WomenhavingapastpregnancymayhavedevelopedtheseantibodiestoMHCantigenscarriedonthefatherscellsorthedevelopingfetus.