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RNA Interference Products

RNA干扰(RNA interference, RNAi)是指在进化过程中高度保守的、由双链RNA(double-stranded RNA,dsRNA)诱发的、同源mRNA高效特异性降解的现象。基因沉默,主要有转录前水平的基因沉默(TGS)和转录后水平的基因沉默(PTGS)两类:TGS是指由于DNA修饰或染色体异染色质化等原因使基因不能正常转录;PTGS是启动了细胞质内靶mRNA序列特异性的降解机制。有时转基因会同时导致TGS和PTGS。
由于使用RNAi技术可以特异性剔除或关闭特定基因的表达,(长度超过三十的dsRNA会引起干扰素毒性)所以该技术已被广泛用于探索基因功能和传染性疾病及恶性肿瘤的治疗领域。


Isotype Control

同型对照

同型对照(Isotype Control),使用与一抗相同种属来源、相同亚型、相同剂量和相同的免疫球蛋白及亚型的免疫球蛋白,用于消除由于抗体非特异性结合到细胞表面而产生的背景染色。

同型对照

同型对照的主要目的是确定一抗的结合是特异性的,而不是非特异性的Fc受体或与其他蛋白的相互作用。还可以用来竞争性的结合抗体,与功能阻断抗体发挥同样的功能。

同型对照要与一抗的来源,Ig分型和标记完全一致。

如果一抗是多抗,可以用an normal serum(与一抗相同的正常血清) (must be the same species as primary antibody)。This control is easy to achieve and can be used routinely in immunohistochemical staining.这个可以咨询试剂商。同型对照为免疫荧光标记中的阴性对照。由于荧光标记单抗的组来源不同,应选用相同来源的未标记单抗作为同型对照来 调整背景染色。举个例子:比如检测一抗为单抗的mouse anti rat CD11b,clone OX-42 purified IgG,那么它的isotype 是mouse IgG2a, 所以可以用purified(纯化的) mouse IgG2a来做OX-42的同型对照(Isotype Control)。一般的的生物技术公司和国内的代理都有出售。

同型对照:是指与MoAb相同的、未免疫小鼠的免疫球蛋白亚类,若使用直接免疫荧光染色法,同型对照也应标记荧光色素,如IgG1 FITC、IgG2a、PE等。主要考虑了细胞的自发荧光、FC受体介导的抗体结合和非特异性抗体结合等影响因素。此外,同型对照与MoAb所标记的荧光 色素、浓度、F:P比值(标记的荧光色素与免疫球蛋白分子的比值)应该相同为最佳,这对准确设定阴性与阳性细胞的界标有重要意义,切忌使用与MoAb不相 匹配的同型对照,最好为同一实验室、采用相同工艺或方法制备(如同一品牌)的产品。


1,25-Dihydroxyvitamin D3 (Calcitriol) ELISA Kit
abx051035 
Quantitative Competitive
Range: 1.56 ng/ml - 100 ng/ml
Sensitivity: 0.94 ng/ml
US$572.75 (96 tests)
 Comparison List
1,25-Dihydroxyvitamin D3 (Calcitriol) ELISA Kit
abx156662 
Quantitative Competitive
Range: 24.7 pg/ml - 2000 pg/ml
Sensitivity: < 9.13 pg/ml
US$812.00 (96 tests)
 Comparison List
1,25-Dihydroxyvitamin D3 (Calcitriol) ELISA Kit
abx350730 
Quantitative Competitive
Range: 7.81 pg/ml - 500 pg/ml
Sensitivity: 4.69 pg/ml
US$572.75 (96 tests)
 Comparison List
Range: 15.6 pg/ml - 1000 pg/ml
Sensitivity: < 3.6 pg/ml
US$572.75 (96 tests)
 Comparison List
1,3-Dipalmitin ELISA Kit
abx258848 
Quantitative Competitive
Range: 12.35 pg/ml - 1000 pg/ml
Sensitivity: < 4.94 pg/ml
US$826.50 (96 tests)
 Comparison List
1,5-Anhydroglucitol (1,5-AG) ELISA Kit
abx150305 
Quantitative Competitive
Range: 1.9 µg/ml - 150 µg/ml
Sensitivity: < 0.7 µg/ml
US$826.50 (96 tests)
 Comparison List
1-Desamino 8D Arginine Vasopressin (DDAVP) ELISA Kit
abx150333 
Quantitative Competitive
Range: 123.5 pg/ml - 10000 pg/ml
Sensitivity: < 39.5 pg/ml
US$826.50 (96 tests)
 Comparison List
1-Desamino 8D Arginine Vasopressin (DDAVP) ELISA Kit
abx574303 
Quantitative Competitive
Range: 12.35 pg/ml - 1000 pg/ml
Sensitivity: < 5.52 pg/ml
US$862.75 (96 tests)
 Comparison List
Range: 1.56 ng/ml - 100 ng/ml
Sensitivity: 0.94 ng/ml
US$681.50 (96 tests)
 Comparison List
11-Dehydrothromboxane B2 (11-Dehydro-TXB2) ELISA Kit
abx255672 
Quantitative Competitive
Range: 15.6 pg/ml - 1000 pg/ml
Sensitivity: 9.38 pg/ml
US$609.00 (96 tests)
 Comparison List
11-Dehydrothromboxane B2 (11-Dehydro-TXB2) ELISA Kit
abx251255 
Quantitative Competitive
Range: 15.6 pg/ml - 1000 pg/ml
Sensitivity: 9.38 pg/ml
US$652.50 (96 tests)
 Comparison List
12-Hydroxyeicosatetraenoic Acid (12-HETE) ELISA Kit
abx251300 
Quantitative Competitive
Range: 0.78 ng/ml - 50 ng/ml
Sensitivity: 0.47 ng/ml
US$572.75 (96 tests)
 Comparison List
12-Hydroxyeicosatetraenoic Acid (12-HETE) ELISA Kit
abx258309 
Quantitative Competitive
Range: 12.35 ng/ml - 1000 ng/ml
Sensitivity: < 5.45 ng/ml
US$826.50 (96 tests)
 Comparison List
12-Hydroxyeicosatetraenoic Acid (12-HETE) ELISA Kit
abx514543 
Quantitative Competitive
Range: 0.156 ng/ml - 10 ng/ml
Sensitivity: 0.09 ng/ml
US$572.75 (96 tests)
 Comparison List
Range: 0.312 ng/ml - 20 ng/ml
Sensitivity: 0.19 ng/ml
US$681.50 (96 tests)
 Comparison List
Description: 14-3-3 beta/zeta Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto..
US$543.75 (96 tests)
 Comparison List
14-3-3 Protein Theta (YWHAQ) ELISA Kit
abx153545 
Quantitative Sandwich
Range: 0.312 ng/ml - 20 ng/ml
Sensitivity: < 0.13 ng/ml
US$797.50 (96 tests)
 Comparison List
14-3-3 Protein Theta (YWHAQ) ELISA Kit
abx156960 
Quantitative Sandwich
Range: 0.156 ng/ml - 10 ng/ml
Sensitivity: < 0.06 ng/ml
US$797.50 (96 tests)
 Comparison List
14-3-3 Protein Zeta/Delta (YWHAZ) ELISA Kit
abx258054 
Quantitative Sandwich
Range: 0.312 ng/ml - 20 ng/ml
Sensitivity: < 0.12 ng/ml
US$797.50 (96 tests)
 Comparison List
Description: 14-3-3 zeta Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a cl..
US$543.75 (96 tests)
 Comparison List
15-Deoxy-delta 12,14-prostaglandin J2 (15d-PGJ2) ELISA Kit
abx351111 
Quantitative Competitive
Range: 3.125 ng/ml - 200 ng/ml
Sensitivity: 1.88 ng/ml
US$282.75 (24 tests)
 Comparison List
17-Hydroxyprogesterone (17-OHP) ELISA Kit
abx150306 
Quantitative Competitive
Range: 246.9 pg/ml - 20000 pg/ml
Sensitivity: < 87.3 pg/ml
US$812.00 (96 tests)
 Comparison List
17-Hydroxyprogesterone (17-OHP) ELISA Kit
abx257402 
Quantitative Competitive
Range: 0.47 ng/ml - 30 ng/ml
Sensitivity: 0.28 ng/ml
US$572.75 (96 tests)
 Comparison List
Range: 31.2 nmol/ml - 2000 nmol/ml
US$572.75 (96 tests)
 Comparison List
2,3-Bisphosphoglycerate (2,3-BPG) ELISA Kit
abx585473 
Quantitative Competitive
Range: 1.23 µg/ml - 100 µg/ml
Sensitivity: < 0.46 µg/ml
US$855.50 (96 tests)
 Comparison List
2-Arachidonoylglycerol (2-AG) ELISA Kit
abx258337 
Quantitative Competitive
Range: 3.7 ng/ml - 300 ng/ml
Sensitivity: < 1.44 ng/ml
US$862.75 (96 tests)
 Comparison List
2-Methoxyestradiol (2-ME2) ELISA Kit
abx257195 
Quantitative Competitive
Range: 61.25 ng/ml - 2000 ng/ml
Sensitivity: < 31 ng/ml
US$543.75 (96 tests)
 Comparison List
25-Hydroxyvitamin D3 (Calcidiol) ELISA Kit
abx150307 
Quantitative Competitive
Range: 2.47 ng/ml - 200 ng/ml
Sensitivity: < 0.91 ng/ml
US$812.00 (96 tests)
 Comparison List
25-Hydroxyvitamin D3 (Calcidiol) ELISA Kit
abx570015 
Quantitative Competitive
Range: 3.125 ng/ml - 200 ng/ml
Sensitivity: 1.88 ng/ml
US$572.75 (96 tests)
 Comparison List
25-Hydroxyvitamin D3 (Calcidiol) ELISA Kit
abx514367 
Quantitative Competitive
Range: 1.56 ng/ml - 100 ng/ml
Sensitivity: 0.94 ng/ml
US$572.75 (96 tests)
 Comparison List
Description: PSMD2 Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear fl..
US$543.75 (96 tests)
 Comparison List
Description: 26S Proteasome Regulatory Subunit 6A (PSMC3) Cell ELISA Kit is a cell-based ELISA Kit. Cells to be a..
US$543.75 (96 tests)
 Comparison List
27-Hydroxycholesterol (27-HC) ELISA Kit
abx257403 
Quantitative Competitive
Range: 15.625 ng/ml - 1000 ng/ml
Sensitivity: < 9.375 ng/ml
US$543.75 (96 tests)
 Comparison List
3-Methoxytyramine (3-MT) ELISA Kit
abx585075 
Quantitative Competitive
Range: 61.7 pg/ml - 5000 pg/ml
Sensitivity: < 23.5 pg/ml
US$862.75 (96 tests)
 Comparison List
3-Methylhistidine (3-MH) ELISA Kit
abx257295 
Quantitative Competitive
Range: 6.25 nmol/ml - 400 nmol/ml
Sensitivity: < 3.75 nmol/ml
US$543.75 (96 tests)
 Comparison List
3-Nitrotyrosine (3-NT) ELISA Kit
abx257155 
Quantitative Competitive
Range: 1.56 ng/ml - 100 ng/ml
Sensitivity: 0.94 ng/ml
US$572.75 (96 tests)
 Comparison List
4-Hydroxynonenal (4-HNE) ELISA Kit
abx257639 
Quantitative Competitive
Range: 0.625 ng/ml - 40 ng/ml
Sensitivity: 0.38 ng/ml
US$572.75 (96 tests)
 Comparison List
4E-BP1 Cell ELISA Kit
abx595006 
Description: 4E-BP1 Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear f..
US$543.75 (96 tests)
 Comparison List
5-Hydroxyeicosatetraenoic Acid (5-HETE) ELISA Kit
abx251443 
Quantitative Competitive
Range: 0.156 ng/ml - 10 ng/ml
Sensitivity: < 0.09 ng/ml
US$572.75 (96 tests)
 Comparison List
5-Hydroxyeicosatetraenoic Acid (5-HETE) ELISA Kit
abx258329 
Quantitative Competitive
Range: 9.88 ng/ml - 800 ng/ml
Sensitivity: < 3.93 ng/ml
US$826.50 (96 tests)
 Comparison List
5-Hydroxyindoleacetic Acid (5-HIAA) ELISA Kit
abx150308 
Quantitative Competitive
Range: 4.94 ng/ml - 400 ng/ml
Sensitivity: < 1.93 ng/ml
US$826.50 (96 tests)
 Comparison List
5-Hydroxyindoleacetic Acid (5-HIAA) ELISA Kit
abx257174 
Quantitative Competitive
Range: 1.56 ng/ml - 100 ng/ml
Sensitivity: 0.94 ng/ml
US$572.75 (96 tests)
 Comparison List
5-Hydroxytryptophan (5-HTP) ELISA Kit
abx156752 
Quantitative Competitive
Range: 4.93 ng/ml - 400 ng/ml
Sensitivity: < 1.94 ng/ml
US$826.50 (96 tests)
 Comparison List
53BP1 Cell ELISA Kit
abx595007 
Description: 53BP1 Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear fl..
US$543.75 (96 tests)
 Comparison List
6-Hydroxydopamine (6-OHDA) ELISA Kit
abx350007 
Quantitative Competitive
Range: 0.156 ng/ml - 10 ng/ml
Sensitivity: 0.1 ng/ml
US$543.75 (96 tests)
 Comparison List
6-Keto-Prostaglandin F1alpha (6-Keto-PGF1alpha) ELISA Kit
abx257166 
Quantitative Competitive
Range: 15.6 pg/ml - 1000 pg/ml
Sensitivity: 9.38 pg/ml
US$572.75 (96 tests)
 Comparison List
Description: 60S Ribosomal Protein L10 Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be se..
US$543.75 (96 tests)
 Comparison List
7-Dehydrocholesterol ELISA Kit
abx150484 
Quantitative Competitive
Range: 2.47 ng/ml - 200 ng/ml
Sensitivity: < 0.94 ng/ml
US$797.50 (96 tests)
 Comparison List
8-Hydroxy-2' -Deoxyguanosine (8-OHdG) ELISA Kit
abx150312 
Quantitative Competitive
Range: 74.1 pg/ml - 6000 pg/ml
Sensitivity: < 26.29 pg/ml
US$812.00 (96 tests)
 Comparison List
8-Hydroxy-2' -Deoxyguanosine (8-OHdG) ELISA Kit
abx257146 
Quantitative Competitive
Range: 1.56 ng/ml - 100 ng/ml
Sensitivity: 0.94 ng/ml
US$572.75 (96 tests)
 Comparison List

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