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公司旨在为客户提供高质量的实验外包服务(CRO服务),包括实验方案设计,常规基因工程实验操作,重组蛋白表达与纯化,重组抗体制备,天然蛋白分离与纯化,病毒分离培养等免疫学相关技术服务;同时我们也为工业客户提供部分IVD级别抗体和抗原原料。核心平台:---噬菌体抗体展示技术平台苏州蚂蚁淘生物科技有限公司利用自有的噬菌体(M13,T7噬菌体)展示技术平台,能够为客户提供极具性价比的重组Vhh抗体(纳米抗体/驼类纳米抗体)制备方案,包括动物免疫,文库建立,文库筛选以及重组抗体的体外表达等。---抗体工程技术平台卡梅德生物科技的抗体工程平台包含单克隆抗体制备服务平台,多克隆抗体制备服务平台,抗体测序与改造平台。单克隆抗体制备平台:基于杂交瘤技术的小鼠单抗技术平台,最快能够在2-3个月获得高亲和力与高特异性的单克隆抗体,同时基于噬菌体展示技术,我司能够制备多物种的重组单克隆抗体,包括小鼠,兔子,骆驼,羊驼以及人单抗。多克隆抗体制备服务平台:能够为客户提供兔多抗,羊多抗,骆驼类多抗,牛多抗等多物种的抗体制备服务,根据不同的抗原类型,来自蚂蚁淘生物的资深抗体专家会为您量身定做适合您需求的方案,以满足您的项目要求并节省您的宝贵时间。抗体一级序列测序平台:为满足大量客户对抗体基因序列与氨基酸序列信息的需求,我们为客户提供DeNovo抗体全长氨基酸序列解析和N端测序服务;同时我们设计积累多达80种杂交瘤抗体基因测序引物。抗体改造技术平台:蚂蚁淘生物技术的抗体改造平台包括嵌合抗体制备,抗体亲和力成熟以及抗体人源化服务。目前我们已经成功制备十几例嵌合抗体与人源化抗体,均成功交付。---蛋白表达与纯化服务技术平台蚂蚁淘生物科技目前拥有四大蛋白表达平台,能为客户提供全面且优质的蛋白表达技术服务。哺乳动物表达平台:目前公司拥有FreestyleCHO,ExpiCHO,CHO-DG44,HEK293F,Vero等细胞系用于蛋白表达制备。公司秉承质量优先原则,全部统一采用Gibco细胞培养基和相关转染配套试剂,以保证每个批次的哺乳动物细胞蛋白表达产品高质量、高表达水平的交付。同时公司拥有的表达载体体系,远高于市面常用蛋白表达载体,能够为客户提供高纯度蛋白。昆虫细胞表达平台:目前公司常采用的昆虫表达细胞为SF9,配套使用的是来自Gibco的培养基,只...


CLIAKits化学发光免疫分析(chemiluminescenceimmunoassay,CLIA)

RNAInterferenceProducts RNA干扰试剂

RNA干扰(RNAinterference,RNAi)是指在进化过程中高度保守的、由双链RNA(double-strandedRNA,dsRNA)诱发的、同源mRNA高效特异性降解的现象。基因沉默,主要有转录前水平的基因沉默(TGS)和转录后水平的基因沉默(PTGS)两类:TGS是指由于DNA修饰或染色体异染色质化等原因使基因不能正常转录;PTGS是启动了细胞质内靶mRNA序列特异性的降解机制。有时转基因会同时导致TGS和PTGS。

由于使用RNAi技术可以特异性剔除或关闭特定基因的表达,(长度超过三十的dsRNA会引起干扰素毒性)所以该技术已被广泛用于探索基因功能和传染性疾病及恶性肿瘤的治疗领域。

1.           RNAi抑制转座子活性

两方面的证据提示转座子活性的抑制与siRNA有关

①发现蠕虫mut-7基因参与RNAi并且与转座子的转座抑制有关;

②在果蝇中,参与RNAi的RNA解螺旋酶Spindle-E的突变将导致该基因引起的基因沉默的缺失,同时提高了反转录转座子活性。

2.           RNAi抵御病毒感染

在拟南芥中研究转基因引起基因沉默时发现,sgs2/sde1基因突变的拟南芥对病毒的侵染表现出高度的敏感性。

3.           RNAi参与异染色质的形成和维持

Hall等研究表明,着丝粒同源重复序列和RNAi组分一起正负调节着异染色质的形成并共同促使异染色质组装成核;Vople等在敲除裂殖酵母(S.pombe)的RNAi途径基因(如Argonaute、Dicer、RDRP)时发现异染色质转录得到的dsRNA可以在RNAi途径的参与下,加工成siRNA,siRNA募集异染色质蛋白1(HP1),然后靶向性引起相应异染色质区域的转基因沉默。

4.           RNAi参与机体的发育调控及生理代谢

RNAi只抑制转录后的基因,所以RNAi在生物体发育学研究中具有优势。Chuang等用RNAi技术进一步证实了AG、CLV3、AP1、PAN等已知功能基因在拟南芥花发育过程中的功能。在RNAi过程中形成的RISC复合物可根据不同情况分别利用siRNA或stRNA行使不同的功能,但最终均导致特定基因沉默。


1,25-DihydroxyvitaminD3(Calcitriol)ELISAKit
abx051035 
QuantitativeCompetitive
Range: 1.56ng/ml-100ng/ml
Sensitivity: 0.94ng/ml
US$572.75(96tests)
 ComparisonList
1,25-DihydroxyvitaminD3(Calcitriol)ELISAKit
abx156662 
QuantitativeCompetitive
Range: 24.7pg/ml-2000pg/ml
Sensitivity: <9.13pg/ml
US$812.00(96tests)
 ComparisonList
1,25-DihydroxyvitaminD3(Calcitriol)ELISAKit
abx350730 
QuantitativeCompetitive
Range: 7.81pg/ml-500pg/ml
Sensitivity: 4.69pg/ml
US$572.75(96tests)
 ComparisonList
Range: 15.6pg/ml-1000pg/ml
Sensitivity: <3.6pg/ml
US$572.75(96tests)
 ComparisonList
1,3-DipalmitinELISAKit
abx258848 
QuantitativeCompetitive
Range: 12.35pg/ml-1000pg/ml
Sensitivity: <4.94pg/ml
US$826.50(96tests)
 ComparisonList
1,5-Anhydroglucitol(1,5-AG)ELISAKit
abx150305 
QuantitativeCompetitive
Range: 1.9µg/ml-150µg/ml
Sensitivity: <0.7µg/ml
US$826.50(96tests)
 ComparisonList
1-Desamino8DArginineVasopressin(DDAVP)ELISAKit
abx150333 
QuantitativeCompetitive
Range: 123.5pg/ml-10000pg/ml
Sensitivity: <39.5pg/ml
US$826.50(96tests)
 ComparisonList
1-Desamino8DArginineVasopressin(DDAVP)ELISAKit
abx574303 
QuantitativeCompetitive
Range: 12.35pg/ml-1000pg/ml
Sensitivity: <5.52pg/ml
US$862.75(96tests)
 ComparisonList
Range: 1.56ng/ml-100ng/ml
Sensitivity: 0.94ng/ml
US$681.50(96tests)
 ComparisonList
11-DehydrothromboxaneB2(11-Dehydro-TXB2)ELISAKit
abx255672 
QuantitativeCompetitive
Range: 15.6pg/ml-1000pg/ml
Sensitivity: 9.38pg/ml
US$609.00(96tests)
 ComparisonList
11-DehydrothromboxaneB2(11-Dehydro-TXB2)ELISAKit
abx251255 
QuantitativeCompetitive
Range: 15.6pg/ml-1000pg/ml
Sensitivity: 9.38pg/ml
US$652.50(96tests)
 ComparisonList
12-HydroxyeicosatetraenoicAcid(12-HETE)ELISAKit
abx251300 
QuantitativeCompetitive
Range: 0.78ng/ml-50ng/ml
Sensitivity: 0.47ng/ml
US$572.75(96tests)
 ComparisonList
12-HydroxyeicosatetraenoicAcid(12-HETE)ELISAKit
abx258309 
QuantitativeCompetitive
Range: 12.35ng/ml-1000ng/ml
Sensitivity: <5.45ng/ml
US$826.50(96tests)
 ComparisonList
12-HydroxyeicosatetraenoicAcid(12-HETE)ELISAKit
abx514543 
QuantitativeCompetitive
Range: 0.156ng/ml-10ng/ml
Sensitivity: 0.09ng/ml
US$572.75(96tests)
 ComparisonList
Range: 0.312ng/ml-20ng/ml
Sensitivity: 0.19ng/ml
US$681.50(96tests)
 ComparisonList
Description: 14-3-3beta/zetaCellELISAKitisacell-basedELISAKit.Cellstobeassayedshouldbeseededonto..
US$543.75(96tests)
 ComparisonList
14-3-3ProteinTheta(YWHAQ)ELISAKit
abx153545 
QuantitativeSandwich
Range: 0.312ng/ml-20ng/ml
Sensitivity: <0.13ng/ml
US$797.50(96tests)
 ComparisonList
14-3-3ProteinTheta(YWHAQ)ELISAKit
abx156960 
QuantitativeSandwich
Range: 0.156ng/ml-10ng/ml
Sensitivity: <0.06ng/ml
US$797.50(96tests)
 ComparisonList
14-3-3ProteinZeta/Delta(YWHAZ)ELISAKit
abx258054 
QuantitativeSandwich
Range: 0.312ng/ml-20ng/ml
Sensitivity: <0.12ng/ml
US$797.50(96tests)
 ComparisonList
Description: 14-3-3zetaCellELISAKitisacell-basedELISAKit.Cellstobeassayedshouldbeseededontoacl..
US$543.75(96tests)
 ComparisonList
Range: 3.125ng/ml-200ng/ml
Sensitivity: 1.88ng/ml
US$282.75(24tests)
 ComparisonList
17-Hydroxyprogesterone(17-OHP)ELISAKit
abx150306 
QuantitativeCompetitive
Range: 246.9pg/ml-20000pg/ml
Sensitivity: <87.3pg/ml
US$812.00(96tests)
 ComparisonList
17-Hydroxyprogesterone(17-OHP)ELISAKit
abx257402 
QuantitativeCompetitive
Range: 0.47ng/ml-30ng/ml
Sensitivity: 0.28ng/ml
US$572.75(96tests)
 ComparisonList
Range: 31.2nmol/ml-2000nmol/ml
US$572.75(96tests)
 ComparisonList
2,3-Bisphosphoglycerate(2,3-BPG)ELISAKit
abx585473 
QuantitativeCompetitive
Range: 1.23µg/ml-100µg/ml
Sensitivity: <0.46µg/ml
US$855.50(96tests)
 ComparisonList
2-Arachidonoylglycerol(2-AG)ELISAKit
abx258337 
QuantitativeCompetitive
Range: 3.7ng/ml-300ng/ml
Sensitivity: <1.44ng/ml
US$862.75(96tests)
 ComparisonList
2-MethoxyestrADIol(2-ME2)ELISAKit
abx257195 
QuantitativeCompetitive
Range: 61.25ng/ml-2000ng/ml
Sensitivity: <31ng/ml
US$543.75(96tests)
 ComparisonList
25-HydroxyvitaminD3(Calcidiol)ELISAKit
abx150307 
QuantitativeCompetitive
Range: 2.47ng/ml-200ng/ml
Sensitivity: <0.91ng/ml
US$812.00(96tests)
 ComparisonList
25-HydroxyvitaminD3(Calcidiol)ELISAKit
abx570015 
QuantitativeCompetitive
Range: 3.125ng/ml-200ng/ml
Sensitivity: 1.88ng/ml
US$572.75(96tests)
 ComparisonList
25-HydroxyvitaminD3(Calcidiol)ELISAKit
abx514367 
QuantitativeCompetitive
Range: 1.56ng/ml-100ng/ml
Sensitivity: 0.94ng/ml
US$572.75(96tests)
 ComparisonList
Description: PSMD2CellELISAKitisacell-basedELISAKit.Cellstobeassayedshouldbeseededontoaclearfl..
US$543.75(96tests)
 ComparisonList
Description: 26SProteasomeRegulatorySubunit6A(PSMC3)CellELISAKitisacell-basedELISAKit.Cellstobea..
US$543.75(96tests)
 ComparisonList
27-Hydroxycholesterol(27-HC)ELISAKit
abx257403 
QuantitativeCompetitive
Range: 15.625ng/ml-1000ng/ml
Sensitivity: <9.375ng/ml
US$543.75(96tests)
 ComparisonList
3-Methoxytyramine(3-MT)ELISAKit
abx585075 
QuantitativeCompetitive
Range: 61.7pg/ml-5000pg/ml
Sensitivity: <23.5pg/ml
US$862.75(96tests)
 ComparisonList
3-Methylhistidine(3-MH)ELISAKit
abx257295 
QuantitativeCompetitive
Range: 6.25nmol/ml-400nmol/ml
Sensitivity: <3.75nmol/ml
US$543.75(96tests)
 ComparisonList
3-Nitrotyrosine(3-NT)ELISAKit
abx257155 
QuantitativeCompetitive
Range: 1.56ng/ml-100ng/ml
Sensitivity: 0.94ng/ml
US$572.75(96tests)
 ComparisonList
4-Hydroxynonenal(4-HNE)ELISAKit
abx257639 
QuantitativeCompetitive
Range: 0.625ng/ml-40ng/ml
Sensitivity: 0.38ng/ml
US$572.75(96tests)
 ComparisonList
Description: 4E-BP1CellELISAKitisacell-basedELISAKit.Cellstobeassayedshouldbeseededontoaclearf..
US$543.75(96tests)
 ComparisonList
5-HydroxyeicosatetraenoicAcid(5-HETE)ELISAKit
abx251443 
QuantitativeCompetitive
Range: 0.156ng/ml-10ng/ml
Sensitivity: <0.09ng/ml
US$572.75(96tests)
 ComparisonList
5-HydroxyeicosatetraenoicAcid(5-HETE)ELISAKit
abx258329 
QuantitativeCompetitive
Range: 9.88ng/ml-800ng/ml
Sensitivity: <3.93ng/ml
US$826.50(96tests)
 ComparisonList
5-HydroxyindoleaceticAcid(5-HIAA)ELISAKit
abx150308 
QuantitativeCompetitive
Range: 4.94ng/ml-400ng/ml
Sensitivity: <1.93ng/ml
US$826.50(96tests)
 ComparisonList
5-HydroxyindoleaceticAcid(5-HIAA)ELISAKit
abx257174 
QuantitativeCompetitive
Range: 1.56ng/ml-100ng/ml
Sensitivity: 0.94ng/ml
US$572.75(96tests)
 ComparisonList
5-Hydroxytryptophan(5-HTP)ELISAKit
abx156752 
QuantitativeCompetitive
Range: 4.93ng/ml-400ng/ml
Sensitivity: <1.94ng/ml
US$826.50(96tests)
 ComparisonList
Description: 53BP1CellELISAKitisacell-basedELISAKit.Cellstobeassayedshouldbeseededontoaclearfl..
US$543.75(96tests)
 ComparisonList
6-Hydroxydopamine(6-OHDA)ELISAKit
abx350007 
QuantitativeCompetitive
Range: 0.156ng/ml-10ng/ml
Sensitivity: 0.1ng/ml
US$543.75(96tests)
 ComparisonList
Range: 15.6pg/ml-1000pg/ml
Sensitivity: 9.38pg/ml
US$572.75(96tests)
 ComparisonList
Description: 60SRibosomalProteinL10CellELISAKitisacell-basedELISAKit.Cellstobeassayedshouldbese..
US$543.75(96tests)
 ComparisonList
7-DehydrocholesterolELISAKit
abx150484 
QuantitativeCompetitive
Range: 2.47ng/ml-200ng/ml
Sensitivity: <0.94ng/ml
US$797.50(96tests)
 ComparisonList
8-Hydroxy-2"-Deoxyguanosine(8-OHdG)ELISAKit
abx150312 
QuantitativeCompetitive
Range: 74.1pg/ml-6000pg/ml
Sensitivity: <26.29pg/ml
US$812.00(96tests)
 ComparisonList
8-Hydroxy-2"-Deoxyguanosine(8-OHdG)ELISAKit
abx257146 
QuantitativeCompetitive
Range: 1.56ng/ml-100ng/ml
Sensitivity: 0.94ng/ml
US$572.75(96tests)
 ComparisonList

Weofferpre-designedsetsof3siRNAoligoduplexestargetinganygeneofinterestinhuman,mouse or rat.

Designedfor maximumpotency andspecificityusingahighlyeffectiveandextensivelytestedalgorithm.

AllsiRNAsaresynthesizedtothe highestqualitystandards andcomewithfullsequenceinformation.

siRNAsarepowerfultoolsforgenesilencingandcanbedeliveredtothetargetcellorhostbytransfection.

siRNAoligoduplexesarequickandeasytouseandcanbeusedbothinvitroandinvivoforrapidandtransientgenesilencingwithoutalteringthehostgenome.


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