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laysanbio特约代理  点击放大 产品型号： 产品报价： 产品特点： laysanbio代理，laysanbio中国代理，laysanbio上海代理，laysanbio总代，laysanbio laysanbio专业代理-上海起发实验试剂有限公司，具体产品信息欢迎电询：4006551678   laysanbio特约代理的详细资料： laysanbio代理，laysanbio中国代理，laysanbio上海代理，laysanbio总代，laysanbio laysanbio专业代理-上海起发实验试剂有限公司，具体产品信息欢迎电询 聚乙二醇类 www.laysanbio.com   上海起发实验试剂有限公司 实验试剂一站式采购服务商 1：强大的进口辐射能力，血清、抗体、耗材、大部分限制进口品等。 2：产品种类齐全，经营超过700多个品牌，基本涵盖所有生物实验试剂耗材。 3：提供加急服务，货品一般1-2周到货。 4：富有竞争力的价格优势，绝大部分价格有优势。 5：多年积累良好的信誉，大部分客户提供货到付款服务。客户包括清华、北大、交大、复旦、中山等100多所高校，ROCHE，阿斯利康、国药、fisher等知名药企。 6：我们还是Santa,Advanced Biotechnologies Inc,Athens Research & Technology,bangs,BBInternational,crystalchem,dianova,FD Neurotechnologies,Inc. FormuMax Scientific,Inc, Genebridege, Glycotope Biotechnology GmbH; iduron,Innovative Research of America, Ludger, neuroprobe,omicronbio, Polysciences,prospecbi, QA-BIO,quickzyme,RESEARCH DIETS,INC,sterlitech；sysy,TriLink BioTechnologies,Inc；worthington-biochem,zyagen等几十家国外公司授权代理。 7：我们还是invitrogen,qiagen,laysanbioam,sigma;neb,roche,merck, rnd,BD, GE,pierce,BioLegend等知名大品牌批发，欢迎合作。 产品相关关键字： laysanbio代理 laysan bio laysan bio LaysanBio LaysanBio总代

来源：作者：人气：809发表时间：2014-11-20 13:33:00【大 中 小】

Laysan Bio 公司简介
作为一家行业领先的生物技术公司，Laysan Bio, Inc.为客户提供用于各种研发平台的新型聚合物。Laysan为学院，研究中心，生物技术和制药研发公司提供目录/定制标准的活性聚（乙二醇）试剂。Laysan供应各种的活性聚合物，快速响应客户需求并提供技术支持。自2006年7月起执业以来，Laysan的业务呈稳步的增长。管理团队和骨干员工已经开发和提供PEG试剂用于7个FDA或欧盟批准的药品或医疗器械，包括Neulasta®, Somavert®, PEGASYS®, PEG-INTRON®, Definity®, Macugen® and DuraSealTM。

修饰性PEG的用途

1、蛋白质类药物PEG修饰： PEG修饰蛋白质药物可以延长药物的半衰期、降低免疫原性，同时最大限度地保留其生物活性。作为治疗药物，经过聚乙二醇(PEG)修饰的蛋白质比未修饰的蛋白质更有效。PEG对蛋白药物修饰途径主要有氨基修饰（包括N端氨基的酰化修饰、赖氨酸侧链氨基的酰化修饰、N端氨基的烷基化修饰）、羧基修饰、巯基修饰等。目前，国内外对PEG修饰蛋白质类药物的研究主要集中于腺苷脱氨酶、天冬酰胺酶、干扰素、粒细胞集落刺激因子、白细胞介素等，更有40多个药物正在进行临床研究。

2、肽类化合物PEG修饰：肽类化合物PEG修饰，如畦降钙素、表皮生长因子的PEG修饰产物的半衰期和生物活性显著高于原型药物。尤其是肽类化合物在聚乙二醇定点修饰方面较蛋白质更易于实现。在肽类化合物的PEG修饰研究中应用最普遍的是mPE

 3、PEG修饰脂质体：普通免疫脂质体由于在血液中的循环半衰期短，易于被清除，限制了其发展。PEG修饰的长循环脂质体，增加了脂质体的血液循环时间，不但能够逃避网状内皮系统的捕获，还能提高脂质体的被动靶向性。已经被广泛用于脂质体药物制剂。

 4、PEG修饰有机小分子药物：很多小分子药物，目前以抗肿瘤药物为多，采用PEG修饰技术，聚乙二醇支载小分子，可以把它的许多优良性质也随之转移到结合物中，使该聚合物具有优异的生物相容性，在体内能溶于组织液中，能被机体迅速排出体外而不产生任何毒副作用。很多抗肿瘤药物通过高分子量PEG修饰，能够达到肿瘤组织的被动靶向给药。

 5、其它应用：PEG修饰亲和配体和辅因子在含水的两相分配系统中应用，用于生物大分子和细胞的纯化和分析。PEG修饰糖类可作为新的药物材料、药物载体。寡核苷酸PEG化可以增加溶解度，增加对核酸酶的抵抗和细胞膜穿透性。生物材料PEG化可以减少血栓形成，降低蛋白质和细胞黏附性。

Laysan Bio Products

Dear Customer,

Laysan Bio is a dedicated supplier and we are taking this opportunity to reassure you that Laysan is taking every precaution and has policies in place to limit the risk of the Covid 19 virus in our workplace.

Laysan Bio is working with our vendors to ensure our supply chain is stable by staying in contact with them to make sure that critical raw materials and supplies needed for manufacturing are in stock and to make sure that lead times do not become a problem.

Thank you for your continued support of Laysan Bio if we can help you in any way please do not hesitate to contact us.

Thank you for your interest in the reagents from Laysan Bio, Inc.  Below is a list of sale items followed by a list of the categories for the reagents that we offer.  To find out more information about using our reagents, please go to our FAQ page.  Click here to download a printable order form.

MONTHLY WEB SALE FOR May:  You must enter the code in the Comments section of the order form online.  You can also send your order through email, by phone, or fax and use this code for a discount.  This code will expire on May 30th.  One code per line item.  Please check back monthly for new product discounts each month.

WS0520-20% (20% discount)     

mPEG2-NHS-40K                                                                                           
                                                                                                 
 DSPE-PEG-MAL-10K   

4 arm PEG-EPOX-20K               

NH2-PEG-CM-10K                                  
 
MPEG-SAS-5000

MPEG-SAS-20K

If you do not see a reagent that will fit your needs, please contact us to receive a custom quotation. If you need a quote for quantities larger than 50 grams, please contact us for bulk pricing. 

Don't know which PEG to use?  Laysan offers research kits to help reduce the cost and time determining which functional group and MW is appropriate for your application. The kits consist of multiple functional groups that will react with a specific targeted end group or with multiple MWs of a single functional group.  Individual kit information is available on our kit page.

We offer smaller bottling requests for a fee of $50 and then $5 per bottle.  Due to the accuracy of our scales, we are not able to bottle lower than 100 mg quantities. 

***We have listed several custom reagents that are frequently in stock.  Please contact us for availability on all reagents.

PLACING ORDERS:  You can use the link within the shopping cart to place an order or you can complete the order form and send it by email (sales@laysanbio.com) or fax (256-586-9007).  Please contact us at sales@laysanbio.com or by phone at 888-852-9726 or 256-586-9004 with any questions prior to placing your order.  If you need to ask a technical question about one of our reagents, please contact us at tech@laysanbio.com.  

REAGENT CATEGORIES
Pegylation Research Kits

Acrylates (ACRL)

Aldehydes (bALD and pALD)

Amines (NH2)

Biotins (BIO)

Carboxymethyl (COOH)

Epoxides (EPOX)

Esters (SC, SCM, SG, SS, SVA)

Hydrazides (HZ)

Hydroxyls (OH)

Maleimides (MAL)

Multi-Arm (4 arm PEG reagents)

Nitrophenyl Carbonates (NPC)

Orthopyridyl Disulfides (OPSS)

Phospholipid (DSPE)

Protected PEGs (FMOC and tBOC)

Silanes (SIL)

Thiols (SH)

Valeric Acid (VA)

All sales are subject to Laysan Bio's Terms and Conditions of Sale.  Please click here to view the Terms and Conditions.  Because of the broad range of uses for PEG reagents, Laysan Bio can not guarantee that the reagent(s) will work for each customer's specific use.  If you have questions we encourage you to contact us prior to ordering the reagent(s). 

All products are shipped overnight or international priority for the stability of the product(s).

International Customers:  If a VAT# or broker information is not included at the time of an international order, a delay may occur. An email address is required so a tracking number can be sent.  The customer is responsible for contacting FedEx if a delay occurs. Laysan is not responsible for deliveries delayed due to international customs issues or weather. Thank you for your cooperation.

Click here to find a listing of our MSDS documents.  Click here to find a listing of our SDS documents.

LAYSAN BIO OFFERS COMPLIANT MANUFACTURING

Laysan Bio has a Quality System and manufactures cGMP compliant “Bulk Pharmaceutical Chemical” reagents.  We welcome all discussions regarding this service and will work with you to help our products fit your project requirements.  If you are not sure if you need compliant-grade or research-grade material, click here for more information.  We have a list of compliant-grade reagents that are currently in stock on the, "Compliant Products In Stock" page.  Call today to request a quotation or to schedule a conference call.