e-coelenterazineorCoelenterazine-E(e-CTZ)isasyntheticanalogueofnativeCoelenterazinewithanadditionalethylgroup,forminganadditionalringsystem.FirstdescribedbyShimomurain1989.
ForRenillamuelleriLuciferase,anincreaseof750%ininitialintensityand137%intotallightwasobservedusinge-CoelenterazinecomparedtonaitveCoelenterazine.
e-CTZisnowavailavleinsterileinjeectionvialswithalowretentionvolume.EachkitissuppledwithtwoInject-A-Lumevialsof500uge-CTZand500ulofsterilFuel-Injectdiluent.Itwasreportedthatthisanalogueenhancesthesignalbytwo-foldinRenillaLuciferaseinvivostudies.
Note:InwillnotbeutilizedbyGaussiaLuciferase.
CompoundID: | e-CoelenterazineorCoelenterazine-E |
CAS#: | 114496-02-5 |
IUPACName: | Benz[f]imidazol[1,2-a]quinoxalin-3(6H)-one,5,11-dihydro-8- hydroxy-2-[(4-hydroxyphenyl0methyl]-12-(phenylmethyl) |
MolecularFormula: | C28H23N203 |
MW: | 449.5 |
Structure: | ![]() |
HowToUseInject-A-Lumee-Coelenterazine
CertificateofAnalysis HPLC MSDS NMR
Shipping:viaFedExorUPSatRT,overnightor2nddelivery.Storeat-20Corbelow
Kitcontent: