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Adipogen/antiIL23p19 (human), mAb (I 178G)/AG20A0027C050/50 µg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Adipogen/antiIL23p19 (human), mAb (I 178G)/AG20A0027C050/50 µg

MoreInformation
ProductDetails
SynonymsInterleukin-23Subunitp19;Interleukin-23Subunitα;IL-23-A
ProductTypeMonoclonalAntibody
Properties
CloneI178G
IsotypeRatIgG2aκ
Immunogen/AntigenRecombinanthumanIL-23p19.
ApplicationELISA:(directorindirect:1:2000-1:10000)
Westernblot:(1:2000-1:10000usingECL.SuggestedblockinganddilutionbufferisTBSTwith0.05%Tween20and5%skimmilk.Suggestedincubationtimeis1houratrooomtemperature).
Optimalconditionsshouldbedeterminedindividuallyforeachapplication.
CrossreactivityHuman
SpecificityRecognizeshumanIL-23p19.
PurityDetailProteinG-affinitypurified.
Concentration1mg/ml
FormulationLiquid.0.2μm-filteredsolutioninPBS,pH7.4.Containsnopreservatives.
ShippingandHandling
ShippingBLUEICE
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceAfteropening,preparealiquotsandstoreat-20°C.
Avoidfreeze/thawcycles.
Use/StabilityStableforatleast1yearafterreceiptwhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
IL-23p19associateswithIL-12btoformtheIL-23interleukin,anheterodimericcytokinewhichfunctionsininnateandadaptiveimmunity.IL-23bindstoanheterodimericreceptorcomplexcomposedofIL-12RB1andIL-23R,activatestheJak-Statsignalingcascade,stimulatesmemoryratherthannaiveT-cellsandpromotesproductionofproinflammatorycytokines.IL-23inducesautoimmuneinflammationandthusmayberesponsibleforautoimmuneinflammatorydiseasesandmaybeimportantfortumorigenesis.

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