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Bpsbioscience/Native Nucleosome (HeLaderived)/52039/0.6 mg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Bpsbioscience/Native Nucleosome (HeLaderived)/52039/0.6 mg
Species:Human
HostSpecies:HeLaCells
Description:
NativenucleosomepurifiedfromhumanHeLacells.
Formulation:
10mMTris-HCl,pH7.2,5mMNaCl,1mMMgCl2,0.5mMCaCl2,125mMEDTA,and10mMSodiumButyrate
Format:
Aqueoussolutionsufficientfor50reactionsina96-wellformat
Storage/StABIlity:
Atleast6monthsat–80°C.
Application(s):
Substrateforhistonemethyltransferaseassays.IdealforscreeningsmallmolecularinhibitorsofhistonemethyltransferasesfordrugdiscoveryandHTSapplications.
Reference(s):

1.Meagher,R.B.,Mussar,K.J.,EpigeneticsChromatin2012Jul20;5(1):11.
2.Huang,H.,etal.,Biosystems2012Aug;109(2):214-9.

ApplicationReference(s):
1.Rapidgenerationofdrug-resistanceallelesatendogenouslociusingCRISPR-Cas9indelmutagenesis(2017)
2. One-potrefoldingofcorehistonesfrombacterialinclusionbodiesallowsrapidreconstitutionofhistoneoctamer(2015)
3.Roleofanon-canonicalsurfaceofRad6inubiquitinconjugatingactivity(2015)

Notes:
TheconcentrationofthisproductisdeterminedbyBradfordandrepresentsonlytheproteinconcentration.
Warning(s):
Avoidfreeze/thawcycles.
ScientificCategory:
Methyltransferase/Substrate
ProductType:
PurifiedProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.

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