pVSVG载体_质粒图谱 优宝生物

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pVSV-G 载体

型号 载体名称 出品公司 载体用途 VMC0386 pVSV-G Clontech 慢病毒包装载体

载体描述:

pVSV-G expresses the G glycoprotein of the vesicular stomatitis virus （VSV-G） under the control of the CMV immediate-early promoter. VSV-G is used in pseudotyping of Moloney Murine Leukenia Virus （MMLV）-based retroviral vectors by mediating viral entry. VSV-G interacts with phospholipid components of the target cell membrane and fosters the fusion of viral and cellular membranes. VSV-G does not require a cell surface receptor and can serve as a surrogate viral envelope protein. pVSV-G Vector includes IVS, a synthetic intron known to enhance the stability of the mRNA, the Col E1 origin of replication and bacterial ampicillin rsistance （Ampr）gene for propagation and antibiotic selection in bacteria.