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cellscript的目标是为临床研究和治疗细胞转化中制造和使用RNA实验中提供的产品和
技术。目前cellscript的产品包括体外转录的RNA试剂盒,多聚腺苷酸化和核苷酸修饰的RNA
的产品等。cellscriptzui近推出的RNA转录试剂盒包含在RNA修饰核苷体外合成,如假尿苷(
Ψ)和或5-甲基(M5C)在相应的U或C正则核苷的地方。cellscript提供细胞RNA相关产品
,产品品质保证,cellscript公司受到了全世界实验室的广泛好评。
cellscript产品报价表如下
货号 品名 CAS 价格 规格 品牌
C-PAP5104H A-Plus?Poly(A)PolymeraseTailingKit 3315 50rxns
cellscript
C-ACM04037 AmpliCap-Max?T7HighYieldMessageMakerKit 5576
25rxns cellscript
C-AC0706 AmpliCap?SP6HighYieldMessageMakerKit 5576
25rxns cellscript
C-C50110 Anti-ReverseCapAnalog(ARCA) 2176 500nmol
cellscript
C-ICSY110510 INCOGNITO?SP6Ψ-RNATranscriptionKit 6205 10rxns
cellscript
C-ICTAMY110510 INCOGNITO?T7ARCA5mC-&Ψ-RNATranscriptionKit
12750 10rxns cellscript
C-ICTMY110510 INCOGNITO?T75mC-&Ψ-RNATranscriptionKit 10455
10rxns cellscript
C-ICTY110510 INCOGNITO?T7Ψ-RNATranscriptionKit 6205 10rxns
cellscript
C-MMA60710 MessageMAX?T7ARCA-CappedMessageTranscriptionKit
4896 10rxns cellscript
C-C61025 MonomethylatedRNACapAnalog 2686 1,250nmol
cellscript
C-PRM101125 PseudoU-RNAMolecularWeightMarkers 4250 25lanes
cellscript
C-SCMT0610 ScriptCap?2'-O-MethyltransferaseKit 1326 10rxns
cellscript
C-SCMT0625 ScriptCap?2'-O-MethyltransferaseKit 3315 25rxns
cellscript
C-SCCE0610 ScriptCap?m7GCappingSystem 3196 10rxns
cellscript
C-SCCE0625 ScriptCap?m7GCappingSystem 6596 25rxns
cellscript
C-SRI6325 ScriptGuard?RNaseInhibitor 1666 2,500units
cellscript
C-SRI6310K ScriptGuard?RNaseInhibitor 4216 10,000units
cellscript
C-AS3106 SP6-Scribe?StandardRNAIVTKit 4046 50rxns
cellscript
C-MSC11610 T7mScript?StandardmRNAProductionSystem 4845
10rxns cellscript
C-MSC100625 T7mScript?StandardmRNAProductionSystem 10625
25rxns cellscript
C-AS2607 T7-Scribe?StandardRNAIVTKit 2635 25rxns
cellscript
C-AS3107 T7-Scribe?StandardRNAIVTKit 4046 50rxns
cellscript
Cellscript™的使命是为临床研究和治疗提供最jia的产品和技术,用于制造和使用RNA在细胞中进行翻译。
目前的产品包括用于体外转录的试剂盒、使用cap模拟物或cap酶的5'RNAcapping和3'RNA聚腺苷酸化的试剂盒,以及用于制造用于细胞翻译的cap、poly(a)-tailmRNA的all-in-one试剂盒。
Cellscript™最近推出了隐身™的体外合成RNA的RNA转录套件包含修饰核苷,如假尿苷(Ψ)和/或5-methylcytidine(m5C)代替相应的U或C规范核苷(图1)。这些工具都取名为“因为封顶,聚腺苷酸和核苷修饰的RNA产物(称为“INCOGNITOmRNAs”)是经过伪装的,因此当它们被转染到表达多种RNA传感器的哺乳动物细胞中时,不会像相应的未经修饰的mrna一样,引发先天免疫反应。
cellscript公司新设代理商
产品清单:
mRNAProduction
T7mScript™StandardmRNAProductionSystem (PDF)
| Simplythebestwaytomake invitro mRNA.Combinesthebenefitsofhigh-yieldtranscriptionwiththoseofpost-transcriptionalcappingandtailingallinonekit.SeeT7-FlashScribeTranscriptionKit,ScriptCapm7GCappingSystem,ScriptCap2'-O-MethyltransferaseKitandA-PlusPoly(A)PolymeraseTailingKitonthispage. |
| C-MSC11610 | 10reactions | $320 |
| C-MSC100625 | 25reactions | $702 |
InVitro Transcription
T7-FlashScribe™TranscriptionKit (PDF)
| Fortheproductionof invitro transcribedRNAwithT7RNApolymeraseandcanonical(GAUC)NTPs.Areactionproduces180µgRNAfrom1µgDNAin 30minutes. |
| C-ASF3507 | 50reactions | $286 |
T7-Scribe™StandardRNAIVTKit (PDF)
| Fortheproductionof invitro transcribedRNAwithT7RNApolymeraseandcanonical(GAUC)NTPs.Areactionproduces150µgRNAfrom1µgDNAin2hours. |
| C-AS3107 | 50reactions | $267 |
SP6-Scribe™StandardRNAIVTKit (PDF)
| Fortheproductionof invitro transcribedRNAwithSP6RNApolymeraseandcanonical(GAUC)NTPs.Areactionproduces90µgRNAfrom1µgDNAin2hours. |
| C-AS3106 | 50reactions | $267 |
Post-TranscriptionalCapping
ScriptCap™m7GCappingSystem (PDF)
| Forpost-transcriptionalcappingof invitro transcribedRNAwithScriptCapCappingEnzyme,GTPandSAM.Cap0(N7-methyl-G)capscanbebuiltwithefficienciesapproaching100%.Thiscannotbeaccomplishedwithco-transcriptionalcappingmethods.UseinconjunctionwithScriptCap2'-O-Methyltransferasetoproduce Cap1caps,thatwhichisfoundonmosteukaryoticmRNAs. |
| C-SCCE0625 | 25reactions | $436 |
ScriptCap™2'-O-MethyltransferaseKit (PDF)
| ForconversionofRNAcontainingCap0capstothosecontainingCap1caps,whicharefoundonmosteukaryoticmRNAs.CanbeusedsimultaneouslywithScriptCapm7GCappingSystemtoproducevirtually100%Cap1-cappedRNAinasinglereaction. |
| C-SCMT0625 | 25reactions | $219 |

CellScript还生产用于传递和翻译的合成修饰mRNA。CELLSCRIPT?最近推出了INCOGNITO?RNA转录试剂盒,用于体外合成含有修饰核苷如假尿苷(Ψ)和/或5-甲基胞苷(m5C)取代相应U或C典型核苷的RNA。这些试剂盒是如此命名的,因为有帽子结构,聚腺苷酸化的和核苷修饰的RNA产物(称为“INCOGNITOmRNA”)是伪装的,因此当转染到哺乳动物细胞时它们不诱导先天免疫应答。