热烈庆祝【广州雅怡生物公司】成为【TransGenic Inc公司】华南区域总代理商

抗体分类

主要产品名

应用对象

AGE/ 内脏脂肪综合症

抗AGEs 单克隆抗体

ü糖尿病等内脏脂肪综合症领域的研究者;             ü化妆品开发研究者(老化因子AGE与抗老化效果的研究)  ;                           ü食品分析研究者(食品中的AGE与糖尿病发病的相关研究)  .                              

※AGE是糖化终末产物（Advanced Glycation End products）的略称。用于糖尿病，动脉硬化阿尔茨海默病 、癌等研究领域。

（包括标记抗体）

葡萄糖由来AGEs ELISA试剂盒

抗CML单克隆抗体

转运体（transporter）

抗人L型氨基酸转运体-1(LAT1)多克隆抗体

ü癌，中枢神经系统疾病的研究者（细胞内摄入氨基酸相关领域）

免疫/ 炎症

抗人Class A 巨噬细胞 清道夫受体

ü免疫及炎症等与机体防御相关的研究  （机体对异物的反应及识别的相关领域）

单克隆抗体

抗人巨噬细胞表面抗原 单克隆抗体

( 例：Clone No. AM-3K )

GPCR

例：抗GPR40 单克隆抗体

ü制药领域的研究者  GPR40是长链脂肪酸的受体，与糖尿病相关。

发育/ 分化

例：抗PDX1 多克隆抗体

ü发育及分化领域的研究者

（在胚胎发育期，从内胚层上皮向消化管上皮分化的过程中的相关分子）

酶

例：抗小鼠Indoleamine-pyrrole 2,3 dioxygenase(IDO)(IDO)

ü免疫抑制酶的研究  （诱导免疫抑制作用的代谢酶）

多克隆抗体

TRP通道

例：抗大鼠TRPV1 (VR-1) 多克隆抗体

ü疼痛的感受性，刺激传导的研究

Cat. No.

Name

categoly

相关研究领域

application reference

KH001

Anti AGE Monoclonal Antibody ( Clone No. 6D12 )

AGEs/Metabolic Syndrome

糖尿病，糖尿病并发症（糖尿病血管病，糖尿病肾病）；神经生物学：衰老，老年性痴呆疾病（阿尔海默氏综合症）

Proc. Natl. Acad. Sci. U. S. A.2006 May 16; 103(20): 7700--7705.
Elimination of damaged proteins during differentiation of embryonic stem cells
Hernebring M, Brolun G, Aguilaniu H, Semb H, Nystrom T.

KT022

Anti Human Class A Macrophage Scavenger Receptor (MSR-A:CD204) Monoclonal Antibody ( Clone No.SRA-E5 )

Immunology/inflammation

免疫及炎症等与机体防御相关的研究;
癌等研究领域

Pathol Int. 2009 May;59(5):300-5.
Detection of M2 macrophages and colony-stimulating factor 1 expression in serous and mucinous ovarian epithelial tumors
Kawamura K, Komohara Y, Takaishi K, Katabuchi H, Takeya M.

KT013

Anti Human Macrophage Surface Antigen Monoclonal Antibody ( Clone No. AM-3K )

Immunology/inflammation

免疫及炎症等与机体防御相关的研究;
癌等研究领域

Cancer Sci. 2010 Oct;101(10):2128-36.
Involvement of M2-polarized macrophages in the ascites from advanced epithelial ovarian carcinoma in tumor progression via Stat3 activation.
Takaishi K, Komohara Y, Tashiro H, Ohtake H, Nakagawa T, Katabuchi H, Takeya M.

KR059

Anti PDX1 Polyclonal Antibody

Development/Differentiation

胰腺发育；胰腺炎；胰腺癌

Antioxid Redox Signal. 2008 Jan;10(1):43-9.
Transgenic expression of antioxidant protein thioredoxin in pancreatic beta cells prevents progression of type 2 diabetes mellitus.
Yamamoto M, Yamato E, Toyoda S, Tashiro F, Ikegami H, Yodoi J, Miyazaki J.

KM112

Anti Rat phospho TRPV1 (VR-1) Polyclonal Antibody

TRP channel

疼痛，刺激传导的研究

Pain. 2006 Jul;123(1-2):106-16
Increased sensitivity of desensitized TRPV1 by PMA occurs through PKCepsilon-mediated phosphorylation at S800.
Mandadi S, Tominaga T, Numazaki M, Murayama N, Saito N, Armati PJ, Roufogalis BD, Tominaga M.

KR101

Anti Mouse Indoleamine-pyrrole 2,3 dioxygenase (IDO) Polyclonal Antibody

Enzyme

-

-

KG133

Anti AGE-4 Monoclonal Antibody ( Clone No. 14B5 )

AGEs/Metabolic Syndrome

糖尿病，糖尿病并发症（糖尿病血管病，糖尿病肾病）；神经生物学：衰老，老年性痴呆疾病（阿尔海默氏综合症

-

KG132

Anti AGE-1 Monoclonal Antibody ( Clone No. 7C1)

AGEs/Metabolic Syndrome

糖尿病，糖尿病并发症（糖尿病血管病，糖尿病肾病）；神经生物学：衰老，老年性痴呆疾病（阿尔海默氏综合症

-

KH024

Anti CML Monoclonal Antibody ( Clone No. NF-1G )

AGEs/Metabolic Syndrome

糖尿病，糖尿病并发症（糖尿病血管病，糖尿病肾病）；神经生物学：衰老，老年性痴呆疾病（阿尔海默氏综合症

Connect Tissue Res. 2007;48(5):271-6.
Amount of N(omega)-(Carboxymethyl)arginine generated in collagen and bovine serum albumin during glycation reactions is significantly different.
Iijima K, Fujimoto D, Irie S.

KG122

Anti AGE-3 Monoclonal Antibody (Clone No. 9D8)

AGEs/Metabolic Syndrome

糖尿病，糖尿病并发症（糖尿病血管病，糖尿病肾病）；神经生物学：衰老，老年性痴呆疾病（阿尔海默氏综合症

-

KH012

Anti Pentosidine Monoclonal Antibody ( Clone No. PEN-12 )

AGEs/Metabolic Syndrome

糖尿病，糖尿病并发症（糖尿病血管病，糖尿病肾病）；神经生物学：衰老，老年性痴呆疾病（阿尔海默氏综合症

Ann N Y Acad Sci. 2008 Apr;1126:328-32.
Modification of vimentin: a general mechanism of nonenzymatic glycation in human skin.
Kueper T, Grune T, Muhr GM, Lenz H, Wittern KP, Wenck H, Stäb F, Blatt T.

KM018

Anti Rat Vanilloid Receptor Subtype1 (VR-1) (capsaicin receptor) Polyclonal Antibody

TRP channel

辣椒素受体;疼痛的感受性，刺激传导的研究

Pain. 2006 Jul;123(1-2):106-16
Increased sensitivity of desensitized TRPV1 by PMA occurs through PKCepsilon-mediated phosphorylation at S800.
Mandadi S, Tominaga T, Numazaki M, Murayama N, Saito N, Armati PJ, Roufogalis BD, Tominaga M.

KH001-A

AGEs-BSA

AGEs/Metabolic Syndrome

-

-

KE026

Anti Human L-type Amino Acid Transporter 1(LAT1) Polyclonal Antibody

Transporter

癌，中枢神经系统疾病

Cancer Lett. 2005 May 26;222(2):237-45.
Amino acid transport system L is differently expressed in human normal oral keratinocytes and human oral cancer cells.
Yoon JH, Kim IJ, Kim H, Kim HJ, Jeong MJ, Ahn SG, Kim SA, Lee CH, Choi BK, Kim JK, Jung KY, Lee S, Kanai Y, Endou H, Kim DK.

KE023

Anti Human　L-type Amino Acid Transporter 1 (LAT1) Monoclonal Antibody ( Clone No. 4D9 )

Transporter

癌，中枢神经系统疾病

-

KE020

Anti Human 4F2 Heavy Chain (4F2hc:CD98) Polyclonal Antibody

Transporter

癌，中枢神经系统疾病

Anticancer Res. 2008 Sep-Oct;28(5A):2649-55.
Characterization of amino acid transport system L in HTB-41 human salivary gland epidermoid carcinoma cells.
Park NS, Kim SG, Kim HK, Moon SY, Kim CS, Cho SH, Kanai Y, Endou H, Kim do K.

KM019

Anti Rat Vanilloid Receptor-like Protein 1 (VRL-1) Polyclonal Antibody

TRP channel

热休克

J Neurosci. 2010 Mar 31;30(13):4601-12.
TRPV2 enhances axon outgrowth through its activation by membrane stretch in developing sensory and motor neurons.
Shibasaki K, Murayama N, Ono K, Ishizaki Y, Tominaga M.

KE021

Anti  Mouse Cystine / Glutamic Acid Transporter (xCT) Polyclonal Antibody

Transporter

-

Am J Pathol. 2007 April; 170(4): 1277--1290.
Glutamate Suppresses Osteoclastogenesis through the Cystine/Glutamate Antiporter
Eiichi Hinoi, Takeshi Takarada, Kyosuke Uno, Maki Inoue, Yasuhiro Murafuji, and Yukio Yoneda

KS129

Anti Human CD98hc(4F2) Monoclonal Antibody (Clone No.WK4)

Transporter

-

-

KM060

Anti Cold / menthol receptor 1(TRPM8) Polyclonal Antibody

TRP channel

热休克、冷休克

Neuroscience. 2005;130(1):223-8.
TRPV2, a capsaicin receptor homologue, is expressed predominantly in the neurotrophin-3-dependent subpopulation of primary sensory neurons.
Tamura S, Morikawa Y, Senba E.

KA009

Anti Metallothionein Monoclonal Antibody ( Clone No. 1A12 )

Environment

环境污染，镉污染,

-

KH010

Anti Pyrraline Monoclonal Antibody ( Clone No. H12 )

AGEs/Metabolic Syndrome

糖尿病，糖尿病并发症（糖尿病血管病，糖尿病肾病）；神经生物学：衰老，老年性痴呆疾病（阿尔海默氏综合症

J. Biochem.2004 Dec;136(6):831-7.
Conventional antibody against Nepsilon-(carboxymethyl)lysine (CML) shows cross-reaction to Nepsilon-(carboxyethyl)lysine (CEL): immunochemical quantification of CML with a specific antibody.
Koito W, Araki T, Horiuchi S, Nagai R.

KT014

Anti Rat Macrophage/Dendritic Cells Monoclonal Antibody ( Clone No. RM-4 )

Immunology/inflammation

免疫

Toxicol Pathol. 2009;37(5):599-605.
Histological and immunohistochemical studies on spontaneous rat astrocytomas and malignant reticulosis.
Nagatani M, Ando R, Yamakawa S, Saito T, Tamura K.

KM037

Anti  PEDF Monoclonal Antibody ( Clone No.14K )

Neuroscience

眼科学，血管重建

KH011

Anti CML Monoclonal Antibody ( Clone No. CMS-10 )

AGEs/Metabolic Syndrome

糖尿病，糖尿病并发症（糖尿病血管病，糖尿病肾病）；神经生物学：衰老，老年性痴呆疾病（阿尔海默氏综合症

Cancer Lett. 2005 May 26;222(2):237-45.
Amino acid transport system L is differently expressed in human normal oral keratinocytes and human oral cancer cells.
Yoon JH, Kim IJ, Kim H, Kim HJ, Jeong MJ, Ahn SG, Kim SA, Lee CH, Choi BK, Kim JK, Jung KY, Lee S, Kanai Y, Endou H, Kim DK.

KT118

Anti Human Macrophage Scavenger Receptor A (MSR- A:CD204) Monoclonal Antibody (Clone No. SRA-C6)

Immunology/inflammation

-

-

KR074

Anti　Keratin 12 Polyclonal Antibody

Development/Differentiation

再生治疗（再生医学）

Ophthalmology. 2006 Oct;113(10):1765-72.
Transplantation of autologous serum-derived cultivated corneal epithelial equivalents for the treatment of severe ocular surface disease.
Nakamura T, Inatomi T, Sotozono C, Ang LP, Koizumi N, Yokoi N, Kinoshita S.

KO402

Anti Mouse Semaphorin 7A Monoclonal Antibody (Clone No. SKK-7)

Neuroscience

-

-