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Stemcell/Anti-Mouse CD11c Antibody, Clone N418/25 u00b5g/60002PB

Overview

The N418 antibody reacts with CD11c (αX integrin), a 150 kDa type 1 transmembrane glycoprotein that associates non-covalently with CD18 (β2 integrin) to form a heterodimeric cell surface adhesion receptor. Through its interaction with ligands such as iC3b, fibrinogen, and CD54, the CD11c/CD18 receptor is involved in several immune response processes, including cell migration, stimulation of cytokine production by monocytes and macrophages, T cell proliferation, leukocyte recruitment, and phagocytosis. In mice, CD11c is expressed on dendritic cells, macrophages, monocytes, granulocytes, NK cells, and a subset of T cells.This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse CD11c Positive Selection Kit II (Catalog #18780).
Subtype:
Primary Antibodies
Target Antigen:
CD11c
Alternative Names:
alphaX integrin, CR4, integrin alphaX chain, p150
Reactive Species:
Mouse
Conjugation:
Biotin; FITC; PE; Unconjugated
Host Species:
Hamster
Cell Type:
Dendritic Cells
Application:
CyTOF; Flow Cytometry; Immunocytochemistry; Immunofluorescence; Immunohistochemistry; Immunoprecipitation
Area of Interest:
Immunology
Clone:
N418
Gene ID:
16411
Isotype:
IgG
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