Polyclonal Antibody to mouse TLR2 (Tolllike receptor 2)

TLR2Antibody

产品名称：TLR2Antibody

产品类别：一抗

品 牌：ABBIOTEC

货 号：251110

规 格：0.1mg

价 格：4110元
克隆类型：   
RabbitPolyclonalAntibody
亚 型：   
RabbitIg
免疫原：   
KLH-conjugatedsyntheticpeptideencompassingasequencewithintheC-termregionofhumanTLR2.
产品描述：   
Toll-likereceptorfamily(TLR)hasafundamentalroleinpathogenrecognitionandactivationofinnateimmunity.TLRsarehighlyconservedfromDrosophilatohumansandsharestructuralandfunctionalsimilarities.TLRsrecognizepathogen-associatedmolecularpatterns(PAMP)thatareexpressedoninfectiousagents,andmediatetheproductionofcytokinesnecessaryforthedevelopmentofeffectiveimmunity.Toll-linereceptor2(TLR2)cooperateswithLY96tomediatetheinnateimmuneresponsetobacteriallipoproteinsandothermicrobialcellwallcomponents.TLR2actsviaMYD88andTRAF6toleadtoNFkBactivation,cytokinesecretionandinflammatoryresponse.TLR2ishighlyexpressedinperipheralbloodleukocytes,inparticularinmonocytes,inbonemarrow,inlymphnodeandinspleen.GeneticvariationsinTLR2areassociatedwithsusceptibilitytoleprosy,duetoMycobacteriumlepraeinfection.
适用物种：   
H,M,R,P,B
应用范围：   
E,WB,IHC
应用说明：   
E:1:500-1:1,000;WB:1:100-1:500;IHC:1:100-1:500
别 名：   
Toll-likereceptor2;Toll/interleukin-1receptor-likeprotein4;CD282;TLR2;TIL4
形 态：   
Eachvialcontains0.1mgIgGin0.1ml(1mg/ml)ofPBSpH7.4,25%glycerol,5mg/mlBSAwith0.09%sodiumazide.AntibodywaspurifiedbyProtein-Aaffinitychromatography.
保存条件：   
Storeat-20°C.Minimizefreeze-thawcycles.Productisguaranteedoneyearfromthedateofshipment.
相关文献：   
[1]FemiaAetal.2012.ResearchArticle.PLoSONE7(1):e2991.PMID#22242189.[2]HuaFetal.2011.JournalofNeuroinflammation.8:8-42.PMID#21549006.[3]KakutaYetal.TransplantInternational.24(5):514-522.PMID#21291499.
产品链接：   http://www.abbiotec.com/antibodies/tlr2-antibody
 

实验图片：
           

ABBIOTEC公司位于生技圣地--美国圣地亚哥，是2007年新成立的一间生物技术公司，其产品在生命科学实验有着广泛的应用；Abbiotec公司专注于开发抗体，多肽，蛋白等试剂和使其不断市场化；Abbiotec的专有技术使其能够高效的挑选，设计和生产抗体，裂解物，以及各种试剂，让研究人员能够更专注于他们的研究。高质量、创新与完整的产品、合理的价格为Abbiotec不变的坚持与承诺；Abbiotec将不断为满足客户的需要和让他们获得最好的成果而努力。|
产品系列：
Antibodies、Peptides、Proteins、Lysates、KitsandReagents