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GeneralInformation |
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Product |
TRPM8AntibodyAffinityPurified |
Description | AffinityPurifiedTransientreceptorpotentialcationchannelsubfamilyMmember8Antibody |
VerifiedApplications | ELISA,WB |
Host | Rabbit |
SpeciesCrossReactivity | Rat,Mouse |
Immunogen | SyntheticpeptidecorrespondingtouniqueaminoacidsequenceonTRPM8protein. |
Accession# | NCBI: NP_599198.2 |
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Quantity |
100µg |
Volume | 200µl |
Concentration | 0.6µg/µlinantibodystABIlizationbuffer |
Form | AffinityPurified |
Clonality | Polyclonal |
Storage | -20⁰Cforlongtermstorage |
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DB | 1:10,000 |
ELISA | 1:10,000 |
WesternBlot | 1:500 |
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Uniprot# |
Q8R455 |
Overview | Involvedindetectionofsensationssuchascoolness,activatedbyicilin,eucalyptol,menthol,coldandmodulationofintracellularpH |
MolecularFunction | Calciumchannelactivity |
SubcellularLocation | cellmembrane,multi-passmembraneprotein,membraneraft.(Note:Localizestomembraneraftsbutisalsoloatedinthecellmembraneoutsideoftheseregionswherechannelresponsetocoldisenhancedcomparedtomembranerafts) |
Expression | Expressedindorsalrootandtrigeminalganglia.Specificallyexpressedinasubsetofsensoryneurons,includingcold-sensitiveneuronsintrigeminalneurons. |
AlternativeNomenclature | Longtransientreceptorpotentialchannel6antibody LTrpC6antibody ShortformoftheTRPM8cationicchannelantibody TransientreceptorpotentialcationchannelsubfamilyMmember8antibody Transientreceptorpotentialp8antibody TRPP8antibody |