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GeneralInformation |
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Product |
Cytokeratin20Antibody |
Description | AffinityPurifiedkeratin,typeIcytoskeletal20AntibodyN-epitope |
VerifiedApplications | ELISA,IP,WB |
Host | Rabbit |
SpeciesCrossReactivity | Human,Monkey,Mouse |
Immunogen | Syntheticpeptidetakenwithinaminoacidregion300-350humankeratin,typeIcytoskeletal20protein. |
Accession# | NCBI: NP_061883.1 |
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Quantity |
100µg |
Volume | 200µl |
Concentration | 0.55-0.75µg/µlinantibodystABIlizationbuffer |
Form | AffinityPurified |
Clonality | Polyclonal |
Determinant | N-epitope |
Storage | -20⁰Cforlongtermstorage |
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DB | 1:10,000 |
ELISA | 1:10,000 |
Immunoprecipitation | 1:150 |
WesternBlot | 1:500 |
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Uniprot# |
P35900 |
Overview | Playsaroleinmaintainingkeratinfilamentorganizationinintestinalepithelia. Whenphosphorlyateditisinvolvedinthesecretionofmucininthesmallintestine. |
MolecularFunction | StructuralconstituentofCytoskeleton;Apoptosis |
SubcellularLocation | Cytoplasm |
Expression | Mainlyexpressedintheitenstinalepithelium,expressedinluminalcellsofcolonicmucosa. AlsoexpressedinMerkelcellsofkeratinzedoralmucosa. |
Structure | HeterotetrameroftwotypeIandtwotypeIIkeratins,associateswithKRT8. |
AlternativeNomenclature | CD20antibody CK20antibody Cytokeratin20antibody K20antibody Keratin20antibody keratin21,rat,homologofantibody Keratinantibody KeratintypeIcytoskeletal20antibody KRT20antibody KRT21antibody ProteinITantibody typeIcytoskeletal20antibody |