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GeneralInformation |
|
Product |
VPS26Antibody |
Description | AffinityPurifiedVacuolarproteinsorting-associatedprotein26AAntibody |
VerifiedApplications | ELISA,IHC,IP,WB |
Host | Rabbit |
SpeciesCrossReactivity | Human,Mouse,Rat |
Immunogen | Syntheticpeptidetakenwithinaminoacids315-375onhumanVPS26protein. |
| |
Quantity |
100µg |
Volume | 200µl |
Concentration | 0.56µg/µlinantibodystABIlizationbuffer |
Form | AffinityPurified |
Clonality | Polyclonal |
Storage | -20⁰Cforlongtermstorage |
| |
DB | 1:10,000 |
ELISA | 1:10,000 |
| Immunoprecipitation | 1:200 |
| Immunohistochemistry | 1:100 |
WesternBlot | 1:500 |
| |
Uniprot# |
O75436 |
Overview | Actsascomponentoftheretromercargo-selectivecomplex(CSC).TheCSCisbelievedtobethecorefunctionalcomponentofretromerorrespectiveretromercomplexvariantsactingtopreventmissortingofselectedtransmembranecargoproteinsintothelysosomaldegradationpathway.TherecruitmentoftheCSCtotheendosomalmembraneinvolvesRAB7AandSNX3. |
MolecularFunction | proteintransporteractivity |
SubcellularLocation | cytoplasm,endosomemembrane,preipheralmembraneprotein(Note:Localizestotubularprofilesadjacenttoendosomes.Predominantlyfoundinearlynotlateendosomes) |
Expression | Down-regulatedinAlzheimerdisease.NopolymorphismorvariantishoweverassociatedwithAlzheimerdiseaseforVPS26A. |
AlternativeNomenclature | FLJ12930antibody FLJ12930antibody HB58antibody Hbeta58antibody Hbeta58homologantibody MGC94168antibody PEP8Aantibody Vacuolarproteinsorting26Aantibody Vacuolarproteinsorting26homologAyeastantibody Vacuolarproteinsortingassociatedprotein26Aantibody Vesicleproteinsorting26Aantibody VPS26antibody VPS26Aantibody |