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GeneralInformation |
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Product |
PDE4BAntibody |
Description | AffinityPurifiedcAMP-specific3,5-cyclicphosphodiesterase4BAntibodyC-epitope |
VerifiedApplications | CM,ELISA,ICC,IF,IHC,IP,WB |
Host | Rabbit |
SpeciesCrossReactivity | Human,Mouse,Rat |
Immunogen | SyntheticpeptidecommontoallPDE4BsubtypestakennearC-terminal |
| Specificity | ThisantibodydetectsallPDE4Bproteins,includingPDE4B1,PDE4B2,PDE4B3,anda66kDaPDE4Bvariant.Itdoesnotcross-reactwithotherPDEfamilymemberssuchasPDE4A,PDE4C,orPDE4D. |
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Quantity |
100µg |
Volume | 200µl |
Concentration | 0.68µg/µlinantibodystabilizationbuffer |
Form | AffinityPurified |
Clonality | Polyclonal |
Determinant | C-epitope |
Storage | -20⁰Cforlongtermstorage |
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ConfocalMicroscopy |
1:250 |
DB | 1:10,000 |
ELISA | 1:10,000 |
Immunocytochemistry | 1:250 |
Immunofluorescence | 1:250 |
Immunohistochemistry | 1:250 |
Immunoprecipitation | 1:350 |
WesternBlot | 1:500-1:1,000 |
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Uniprot# |
Q07343 |
Overview | HydrolyzesthesecondmessengercAMP,whichisakeyregulatorofmanyimportantphysiologicalprocesses.Maybeinvolvedinmediatingcentralnervoussystemeffectsoftherapeuticagentsrangingfromantidepressantstoantiasthmaticandanti-inflammatory |
MolecularFunction | Hydrolase,3,5-cyclic-AMPphosphodiesteraseactivity,cAMPbinding |
Expression | Expressedinbrain,heart,lungandskeletalmuscle. |
AlternativeNomenclature | 5-cyclicphosphodiesterase4Bantibody cAMP-specific3antibody cAMP-specific3,5-cyclicphosphodiesterase4Bantibody DPDE4antibody dunce-likephosphodiesteraseE4antibody MGC126529antibody PDE4Bantibody PDEIVBantibody PDE32antibody PDE4B5antibody PDEIVBantibody Phosphodiesterase4Bantibody Phosphodiesterase-4BcAMP-specific(dunce(Drosophila)-homolog)antibody |