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GeneralInformation |
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Product |
TLR12AntibodyAffinityPurified |
Description | AffinityPurifiedToll-likereceptor12Antibody |
VerifiedApplications | ELISA,WB |
Host | Rabbit |
SpeciesCrossReactivity | Chimpanzee,Human,Monkey |
Immunogen | Syntheticpeptidetakenwithinaminoacidregion440-470frommouseTLR12protein. |
Accession# | NCBI: NP_991392.1 |
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Quantity |
100µg |
Volume | 200µl |
Concentration | 0.55-0.69µg/µlinantibodystabilizationbuffer |
Form | AffinityPurified |
Clonality | Polyclonal |
Storage | -20⁰Cforlongtermstorage |
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DB | 1:20,000 |
ELISA | 1:20,000 |
WesternBlot | 1:500 |
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Uniprot# |
Q6QNU9 |
Overview | Participatesintheinnateimmuneresponsetomicrobialagents.ActsviaMYD88andTRAF6,leadingtoNF-kappa-Bactivation,cytokinesecretionandtheinflammatoryresponse(Bysimilarity). |
MolecularFunction | Receptor |
SubcellularLocation | Membrane;Single-passtypeImembraneprotein |
Expression | Macrophages,liver,kidneyandbladderepithelialcells. |
Structure | BindsMYD88viatheirrespectiveTIRdomains. |
AlternativeNomenclature | Toll-likereceptor12 |