FabGennix/TDRD7 Antibody/TDRD7701AP/

GeneralInformation

Product

TDRD7Antibody

Description

Tudordomain-containingprotein7isoform1Antibody

VerifiedApplications

ELISA,WB

Host

Rabbit

SpeciesCrossReactivity

Human,Mouse,Rat

Immunogen

Syntheticpeptidetakenwithinthelast50aminoacidsoftheC-terminalendofTDRD7protein.

Accession#

NCBI: NP_055105.2

PhysicalProperties

Quantity

100µg

Volume

200µl

Concentration

0.59-0.62µg/µlinantibodystabilizationbuffer

Clonality

Polyclonal

Storage

-20⁰Cforlongtermstorage

ApplicationProtocol

DB

1:10,000

ELISA

1:10,000

WesternBlot

1:500

Protein

Uniprot#

Q8NHU6

Overview

ComponentofspecificcytoplasmicRNAgranulesinvolvedinpost-transcriptionalregulationofspecificgenes:probablyactsbybindingtospecificmRNAsandregulatingtheirtranslation.Requiredforlenstransparencyduringlensdevelopment,byregulatingtranslationofgenessuchasCRYBB3andHSPB1inthedevelopinglens.Alsorequiredduringspermatogenesis.

MolecularFunction

mRNAbinding

SubcellularLocation

cytoplasm(Note:LocalizestocytoplasmicRNAgranules.Presentinchromatoidbody(CB)ofspermatids(mammaliancounterpartofgermplasm,poleplasmorpolargranulesinDrosophilagermcells),alsonamedprocessingbodies(P-bodies)insomaticcells.De

AlternativeNomenclature

KIAA1529antibody

PCTAIRE2antibody

PCTAIRE2BPantibody

RP11-508D10.1antibody

TDRD7antibody

TrAPantibody

Tudordomaincontaining7antibody

TudorrepeatassociatorwithPCTAIRE2antibody