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GeneralInformation |
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Product |
TLR1Antibody |
Description | AffinityPurifiedToll-likereceptor1 Antibody |
VerifiedApplications | ELISA,IHC,IP,WB |
Host | Rabbit |
SpeciesCrossReactivity | Mouse,Rat Predicted:Human |
Immunogen | Syntheticpeptidetakenwithinaminoacidregion200-250onmousetoll-likereceptor1protein. |
Accession# | NCBI: NP_109607.1 |
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Quantity |
100µg |
Volume | 200µl |
Concentration | 0.55-0.67µg/µlinantibodystabilizationbuffer |
Immunoglobulin | IgG |
Form | AffinityPurified |
Clonality | Polyclonal |
Storage | -20⁰Cforlongtermstorage |
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ELISA |
1:20,000 |
Immunocytochemistry | 1:100 |
Immunofluorescence | 1:100 |
Immunohistochemistry | 1:100 |
Immunoprecipitation | 1:200 |
WesternBlot | 1:500 |
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Uniprot# |
Q9EPQ1 |
Overview | Participatesintheinnateimmuneresponsetomicrobialagents.Specificallyrecognizesdiacylatedandtriacylatedlipopeptides.CooperateswithTLR2tomediatetheinnateimmuneresponsetobacteriallipoproteinsorlipopeptides. |
MolecularFunction | Receptor,Transmembranesignalingreceptoractivity,triacyllipopeptidebinding |
SubcellularLocation | Cellmembrane;Single-passtypeImembraneprotein,Cytoplasmicvesicle> phagosomemembrane;Single-passtypeImembraneprotein |
Structure | BindsMYD88(viaTIRdomains)(Bysimilarity).Interacts(viaextracellulardomain)withTLR2.LigandbindinginducestheformationofaheterodimerwithTLR2(Bysimilarity).InteractswithCNPY3. |
AlternativeNomenclature | CD281antibody KIAA0012antibody LPRS5antibody rsc786antibody SimilartoDrosophilaTollproteinantibody TILantibody TIL.LPRS5antibody Tlr1antibody Toll(Drosophila)homologantibody Tolllikereceptor1antibody Toll/Interleukin1receptorlikeantibody |