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FabGennix/Galectin 3 Antibody/CBP35101AP/

General Information

 

 

Product

 

Galectin 3 Antibody N-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

N-epitope synthetic peptide taken within amino acid sequences 1-100 on human Galectin 3 protein.


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20C for long term storage


Application Protocol

 

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation 1:200

Western Blot

1:500


Protein

 

 

Uniprot #

 

P17931

Overview

Galactose-specific lectin which binds IgE.  Mediates the alpha-3, beta-1 integrin the stimulation CSPG4 of endothelial cells migration.  Invovled in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

Molecular Function

IgE-binding protein, Lectin

Subcellular Location

Cytoplasm; Nucleus; Secreted

Expression

Found in colonic epithelium.  Abundant in activated macrophages.  Expressed in fetal membranes.

Structure

Probably forms homodimer or heterodimers.  Forms complex with the ITGA3, ITGB1 and CSPG4.

Alternative Nomenclature

35 kDa lectin antibody

Carbohydrate-binding protein 35 antibody

CBP 35 antibody

GAL3 antibody

Galactose specific lectin 3 antibody

Galactoside-binding protein antibody

GALBP antibody

GALIG antibody

GBP antibody

IgE binding protein antibody

L 31 antibody

L 34 antibody

Laminin-binding protein antibody

Lectin galactose binding soluble 3 antibody

Lectin L-29 antibody

Lectin, galactose binding, soluble 3 antibody

LGALS 3 antibody

LGALS2 antibody

MAC 2 antigen antibody

Macrophage galactose-specific lectin antibody

Protein information supplied by UniProt
 

 


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