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#6100人主动脉内皮细胞ScienCell原代细胞188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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#6100人主动脉内皮细胞ScienCell原代细胞

产品名称:人主动脉内皮细胞英文名称:Human Aortic Endothelial Cells货号:6100品牌:ScienCell产地:美国规格:5 x10^5,1ml价格:$645

产品说明       主动脉是人体内最大的动脉,把含氧的血液由心脏输送到全身各个部位。位于血管壁的主动脉内皮细胞(AEC)经常暴露于高血流动力,诱导内皮源性血管收缩和血管生长调节的物质生产变化。AEC也调节细胞粘附分子的表达来控制和微调的炎症反应和纤溶系统。这些生理特征使得AEC广泛被应用于研究内皮功能障碍机理、血管疾病和动脉硬化的发病机理、以及新的疾病的治疗技术的发展。      Sciencell研究实验室的ACE是从人主动脉分离得到的,原代冻存,冰冻运输。每管细胞密度超过5×10^5/ml。细胞特性经vWF/Factor VIII和CD31 (PECAM) 免疫荧光鉴定,能够摄取DiI标记乙酰化低密度脂蛋白(DiI-Ac-LDL)。本细胞经检测不含HIV-1、HBV、HCV、支原体、细菌、酵母菌和真菌。如采用ScienCell 实验室特制的培养基,可保证此细胞10倍增增殖。推荐培养基内皮培养基(货号:1001 )

使用说明人主动脉内皮细胞 仅用于科研。不能用于人或动物和体外诊断应用。

储存接收到冻存细胞时请立即从干冰转入液氮中保存。

运输干冰运输。

文献1.) Zhao N, Watson N, Xu Z, Chen Y, Waterman J, Sankar J, Zhu D. (2014) "In Vitro Biocompatibility and Endothelialization of Novel Magnesium-Rare Earth Alloys for Improved Stent Applications." PloS one. 9: e98674.2.) Wang W, Deng M, Liu X, Ai W, Tang Q, Hu J. (2011) "TLR4 Activation Induces Nontolerant Inflammatory Response in Endothelial Cells." Inflammation. 34: 509-18.3.) Cai W, Torreggiani M, Zhu L, Chen X, He JC, Striker GE, Vlassara H. (2010) "AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: implications for vascular disease." Am J Physiol Cell Physiol. 298: C624-34.4.) Kong DK, Georgescu SP, Cano C, Aronovitz MJ, Iovanna JL, Patten RD, Kyriakis JM, Goruppi S. (2010) "Deficiency of the transcriptional regulator p8 results in increased autophagy and apoptosis, and causes impaired heart function." Mol Biol Cell. 21: 1335-49.5.) Shahani T, Lavendhomme R, Luttun A, Saint-Remy JM, Peerlinck K, Jacquemin M. (2010) "Activation of human endothelial cells from specific vascular beds induces the release of a FVIII storage pool." Blood. 115: 4902-9.6.) Zhang CL, Song F, Zhang J, Song QH. (2010) "Hypoxia-induced Bcl-2 expression in endothelial cells via p38 MAPK pathway." Biochem Biophys Res Commun. 394: 976-80.7.) Linden E, Cai W, He JC, Xue C, Li Z, Winston J, Vlassara H, Uribarri J. (2008) "Endothelial dysfunction in patients with chronic kidney disease results from advanced glycation end products (AGE)-mediated inhibition of endothelial nitric oxide synthase through RAGE activation." Clin J Am Soc Nephrol. 3: 691-8.8.) Zhang X, Baughman CB, Kaplan DL. (2008) "In vitro evaluation of electrospun silk fibroin scaffolds for vascular cell growth." Biomaterials. 29: 2217-27.9.) Gentry M, Taormina J, Pyles RB, Yeager L, Kirtley M, Popov VL, Klimpel G, Eaves-Pyles T. (2007) "Role of Primary Human Alveolar Epithelial Cells in Host Defense against Francisella tularensis Infection." Infect Immun. 75: 3969-78.10.) Simard JM, Tsymbalyuk O, Ivanov A, Ivanova S, Bhatta S, Geng Z, Woo SK, Gerzanich V. (2007) "Endothelial sulfonylurea receptor 1-regulated NCCa-ATP channels mediate progressive hemorrhagic necrosis following spinal cord injury." J Clin Invest. 117: 2105-13. 

 

 

 

 

 


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