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Anti-SPIRE2抗体
| 产品编号 | YB-17678R |
| 英文名称 | SPIRE2 |
| 中文名称 | SPIRE2蛋白抗体 |
| 别 名 | MGC117166;Proteinspirehomolog2;Spir-2;SPIR2_HUMAN;Spirehomolog2(Drosophila);SPIRE2. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 肿瘤 细胞生物 神经生物学 信号转导 细胞骨架 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） notyettestedinotherapplications.optimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
| 分 子 量 | 80kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | LyophilizedorLiquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLHconjugatedsyntheticpeptidederivedfromhumanSPIRE2:231-330/714 |
| 亚 型 | IgG |
| 纯化方法 | affinitypurifiedbyProteinA |
| 储 存 液 | 0.01MTBS(pH7.4)with1%BSA,0.03%Proclin300and50%Glycerol. |
| 保存条件 | Storeat-20°Cforoneyear.Avoidrepeatedfreeze/thawcycles.Thelyophilizedantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20°C.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibodytheantibodyisstableforatleasttwoweeksat2-4°C. |
| PubMed | PubMed |
| 产品介绍 | background:Spir-2isa714aminoacidproteinbelongingtothespirefamily.Spir-2isacytoplasmicproteinthatcontainsoneKINDdomainandthreeWH2domains.Spir-2bindstoactinviatheWH2domainsandactsasanactinnucleationfactor.Spir-2isinvolvedinvesicletransportandactsasalinkbetweenactinorganizationandintracellulartransport.Spir-2isexpressedasfourisoformsthatareproducedbyalternativesplicingevents.ThegenethatencodesSpir-2mapstohumanchromosome16,whichencodesover900genesandapproximately90millionbasepairs,makingupnearly3%ofhumancellularDNA.TheGANgeneislocatedonchromosome16and,withmutation,mayleadtogiantaxonalneuropathy,anervoussystemdisordercharacterizedbyincreasingmalfunctionwithgrowth.TheraredisorderRubinstein-Taybisyndromeisalsoassociatedwithchromosome16,thoughthroughtheCREBBPgenewhichencodesacriticalCREBbindingprotein.SignsofRubinstein-Taybiincludementalretardationandpredispositiontotumorgrowthandwhitebloodcellneoplasias.Crohnsdiseaseisagastrointestinalinflammatoryconditionassociatedwithchromosome16throughtheNOD2gene.Function:Actsasaactinnucleationfactor,remainsassociatedwiththeslow-growingpointedendofthenewfilament.Involvedinvesicletransportprocessesprovidinganovellinkbetweenactinorganizationandintracellulartransport.SubcellularLocation:Cytoplasm>Cytoskeleton.Similarity:Belongstothespirefamily.Contains1KINDdomain.Contains3WH2domains.SWISS:Q8WWL2GeneID:84501Databaselinks: EntrezGene:84501 Human EntrezGene:234857 Mouse EntrezGene:307925 Rat Omim:609217 Human SwissProt:Q8WWL2 Human SwissProt:Q8K1S6 Mouse Unigene:461786 Human ImportantNote:Thisproductassuppliedisintendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplications. |
| 产品图片 |  Sample: Liver(Mouse)Lysateat40ugPrimary:Anti-SPIRE2(bs-17678R)at1/300dilutionSecondary:IRDye800CWGoatAnti-RabbitIgGat1/20000dilutionPredictedbandsize:80kDObservedbandsize:80kD |