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Innovative Research/Rat PAI-1 NBD Labeled at the Scissile Bond of the Reactive Center Loop/IRPAI-P1NBD/1.0mg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Innovative Research/Rat PAI-1 NBD Labeled at the Scissile Bond of the Reactive Center Loop/IRPAI-P1NBD/1.0mg

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RatPAI-1NBDlabeledatthescissilebondofthereactivecenterloop

P1"-NBDratPAI-1wascreatedbymutagenesisofthemethionineresidue(Met348)attheP1-P1"scissilebondtocysteine.ThisprovidesafreethiolgroupforlabelingwithNBD,afluorescentprobehighlysensitivetochangesinsolvationandhydrophobicenvironment.ThefluorescenceemissionofP1"-NBDPAI-1isquencheduponcleavageofthereactivecenterloopbyatargetproteinase.ThisuniqueproductisanidealreagentforresearchersstudyingPAI-1behaviorinratmodels.

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