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echelon-inc/Bilirubin Conjugate/1g/F-H130-1g

http://www.Echelon-inc.com/
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CatalogNo.: F-H130
MW: 842.91

Description: BilirubinConjugateisawatersolubleditauratederivativeofbilirubinequivalenttobilirubinglucuronidederivatives.Bilirubinglucuronidederivativesareproducedinvivofromtheglucuronidation(additionofoneortwoglucuronicacidsthroughaglycosidicbond)ofbilirubin(alsocalledindirectbilirubin)inareactioncatalyzedbytheenzymeUDPGlucuronidase.Theglucuronidationofbilirubinoccursinthelivertoformthewatersolublebilirubinmonoordiglucuronide(alsocalledbilirubinconjugateordirectbilirubin).Bilirubinconjugateisexcretedfromtheliverinbileorisconvertedtourobilinogenandexcretedintheurineasurobilinorinthefecesasstercobilin.

Storage

Bilirubinconjugateisstableforatleastoneyearwhenstoredasasolid,protectedfrommoisture,at-20°C.Protectfromlight.

References

1)http://www.echelon-inc.com/Maghzal,G.J.,M.-C.Leck,etal.(2009)."LimitedRolefortheBilirubin-BiliverdinRedoxAmplificationCycleintheCellularAntioxidantProtectionbyBiliverdinReductase."JournalofBIOLOGicalChemistry284(43):29251-29259.
2)http://www.echelon-inc.com/MacLean,P.D.,E.C.Drake,etal.(2007)."Bilirubinasanantioxidantinmicellesandlipidbilayers:Itscontributiontothetotalantioxidantcapacityofhumanbloodplasma."FreeRADIcalBiologyandMedicine43(4):600.
3)McCann,K.B.,Y.Vucica,etal.(2009)."Effectofprocessingmethodsoncolourationofhumanserumalbuminpreparations."Biologicals37(1):32.
4)Bulmer,A.C.,K.Ried,etal.(2007)."Theanti-mutagenicandantioxidanteffectsofbilepigmentsintheAmesSalmonellatest."MutationResearch/GeneticToxicologyandEnvironmentalMutagenesis629(2):122.

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