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SPIbio/Nitazoxanide/10 mg/13692

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Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • 2-(acetyloxy)-N-(5-nitro-2-thiazolyl)-benzamide
Correlated keywords:
  • antiparasitics Giardia Cryptosporidium tuberculosis inhibitors inhibits inhibition PH 6776 alinia BRN 1225475 cryptaz NTZ anti-parasitics Thiazoles
Product Overview:Nitazoxanide (NTZ) is a broadly applicable antiparasitic compound that is rapidly metabolized to tizaxonide whereupon it enters cells and inhibits pyruvate-ferredoxin oxidoreductase.{17926} NTZ demonstrates IC50 values of 2.5 and 10 µM for Giardia and Cryptosporidium, respectively. Additionally, NTZ kills replicating and nonreplicating M. tuberculosis with an IC50 value of 1 µM, while seemingly evading the development of resistance.{17926}
Size 10 mg
Shipping dry ice
Stability Store at -20 degrees; shelf life 730 days
CAS Number 55981-09-4
Molecular Formula C12H9N3O5S
SMILES O=C(NC1=NC=C([N+]([O-])=O)S1)C2=C(OC(C)=O)C=CC=C2
Molecular Weight 307,3
Formulation A crystalline solid
Purity ≥95%
Custom Code 2918.99
UNSPSC code 12352100
Technical File
MSDS

Cayman Chemical"s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

AccreditationsISO/IEC 17025:2005ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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