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dianova/Annexin V FITC (CE-IVD) (200 Tests)/1 ml/ANXVF-200T

  • Übersicht
    ArtikelnummerANXVF-200T
    Artikelgruppe

    Apoptose (FACS), Nachweisreagenz

    Artikelbezeichnung

    Annexin V FITC

    Testprinzip

    Nachweis von Phosphatidylserin auf apoptotischen Zellen, optimiertes Reagenz für die Anwendung in der Durchflusszytometrie

    Inhalt

    rekombinantes Annexin V FITC

    Probenvolumen

    1 Mio. Zellen / Test, 5µl/1 Mio. Zellen

    Zweckbestimmung

    für In-vitro-Diagnostik

    Temperatur - Lagerung

    2-8°C, im Dunkeln

    Temperatur - Transport

    auf Kühlpacks

    Packungsgröße

    200 Tests

    Hersteller / Marke

    ImmunoStep

  • Datenblätter
    • ANXVF-200T – Datenblatt
    • Flyer Apoptose-Assays Immunostep
  • Weitere Produktinformationen
    Apoptosis is characterized by a variety of morphological features. One of the earliest indications of apoptosis is the translocation of the membrane phospholipid phosphatidylserine (PS) from the inner to the outer leaflet of the plasma membrane. Once exposed to the extracellular environment, binding sites on PS become available for Annexin V, a 35-36 kDa, Ca 2+-dependent, phospholipid binding protein with a high affinity for PS. The translocation of PS precedes other apoptotic processes such as loss of plasma membrane integrity, DNA fragmentation, and chromatin condensation. As such, Annexin V can be conjugated to biotin or to a fluorochrome , and used for the easy, flow cytometric identification of cells in the early stages of apoptosis. Aplication Reference;
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