Product name | Hyaluronic Acid - Hyaluronan (HA) ELISATechnical Bulletin | ||||||||||||
Cat-Nr. | TE1017-2 | ||||||||||||
Range | 15 – 1000 ng/mL (Pharmacopeia Standard)LOD: . 2.7 ng/mlLLOQ:15 ng/mlULOQ:1000 ng/ml | ||||||||||||
Sensitivity | 10 ng/ml | ||||||||||||
Incubation time | 3 hours | ||||||||||||
Sample volume | 100 µl | ||||||||||||
Sample type | Serum, EDTA-plasma and cell culture supernatant | ||||||||||||
Sample preparation | Fasting blood collection. Serum or EDTA Plasma stable for 72 hoursat 2-8 °C, 6 months at -20°C, longer storage at -80°C. Maximum 3 freeze- and thaw cycles. | ||||||||||||
Reference values | Hyaluronic Acid Values are dependent on age andgender and influenced by food intake and physical activity. Clinically Healthy Subjects n=53 between 16 and 79 years. 36.7± 23.5 ng/ml.
Cutoff 90 ng/ml± 2 SD | ||||||||||||
Species | Human | ||||||||||||
Tests | 96 Tests | ||||||||||||
Method | ELISA | ||||||||||||
Intended use | Diagnosis and monitoring of liver fibrosis and cirrhosis Diagnosis and monitoring of joint diseases HA is also important in diabetes, as a tumor marker and in pulmonary infections. | ||||||||||||
Product informations | Kit Instructions (PDF 684,0 kB) Technical Bulletin (PDF 2,7 MB) Cross-reaction all species (PDF 70,3 kB) Hyaluronic Acid (Hyaluronan) (PDF 1,6 MB) Bone & Cartilage Metabolism (PDF 1,8 MB) Cartilage Monograph (PDF 2,0 MB) (PDF 2,0 MB) | ||||||||||||
Hyaluronic acid (HA), also known as hyaluronan or hyaluronate is synthesized by fibroblasts and other specialized connective tissue cells and is a major component of connective tissues and thus distributed ubiquitously in the organism. HA can act as a biomarker for joint diseases and correlates in RA and OA patients with the degree of joint inflammation, synovial proliferation and the degree of joint space narrowing. Due to the decreased capacity for hyaluronan clearance, HA is an important biomarker for most chronic liver diseases which are characterised by fibrosis and cirrhosis. Our Hyaluronic Acid PLUS ELISA is suited for the determination of hyaluronic acid in plasma, serum and other biological fluids. |
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