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| Product name | Complement factor H |
| Cat-Nr. | A040 |
| Range | 6 – 230 ng/mL |
| Sensitivity | 3.9 ng/mL (Detection limit)LOD 3.15 ng/mLLLOQ 4.64 ng/mL |
| Incubation time | 2.5 hours |
| Sample volume | 10 µl (dilution 1:5000) |
| Sample type | Serum, EDTA-Plasma Do not use hemolyzed, hyperlipemic, heat-treated or contaminated samples |
| Sample preparation | Samples are stable for 4 hours at 4°C, for longer storage keep at -70°C Avoid multiple freeze-thaw cycles |
| Reference values | Serum – 108 to 510 µg/mL EDTA Plasma – 138 to 489 µg/mL |
| Species | Human |
| Cross reaction | Cross-reactivities for other species or proteins/peptides has not been tested |
| Tests | 96 |
| Method | ELISA |
| Intended use | Complement factor H (CFH) is the first regulatory protein of the alternative pathway of the complement system. Factor H regulates complement both in fluid phase and on cellular surfaces. Genetic analyses reveal a clear association of CFH with different human diseases. Mutations on Factor H result in pathology involving complement activation: aHUS Age-related macular degeneration Dense deposit disease Factor H is a direct modulator of cellular functions by binding to receptors: influences cellular interaction phagocytosis antimicrobial activities Complement factor H (CFH) is the first regulatory protein of the alternative pathway of the complement system. Factor H regulates complement both in fluid phase and on cellular surfaces. Genetic analyses reveal a clear association of CFH with different human diseases. Mutations on Factor H result in pathology involving complement activation: aHUS Age-related macular degeneration Dense deposit disease Factor H is a direct modulator of cellular functions by binding to receptors: influences cellular interaction phagocytosis antimicrobial activities |
| Product informations | Kit Instructions (PDF 479,3 kB) Cross-reaction all species (PDF 70,3 kB) |
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