Moscerdam 代理品牌 上海钰博生物科技有限公司 Powered by...

Moscerdam History of Moscerdam Substrates MoscerdamSubstrates has been the pioneer for novel substrates for lysosomal enzymes for the last 15 years. During this period all the conventional, cumbersome assays for lysosomal enzymes with radio-labelled substrates have been replaced by robust, fluorogenic assays. The range of substrates was developed in a scientific collaboration between the Institute of Organic Chemistry, Russian Academy of Sciences, Moscow and the Metabolic Unit of the Erasmus MC, Rotterdam, the Netherlands. Quality Control Moscerdamsubstrates are not only of high chemical purity, but more importantly are biochemically pure. Enzyme laboratory practice has shown that chemical purity does not always guarantee optimal performance of enzyme assays. Traces of impurity ( 1%) can severely jeopardise results. All Moscerdam substrates are tested with fibroblasts from patients with the corresponding lysosomal storage disease. This biochemical testing is the only way to ensure constant high-quality substrates.The tests are performed in the Department of Medical Biochemistry, headed by Prof. Hans Aerts at the Academic Medical Centre in Amsterdam in the Netherlands. This department has a long standing experience with lysosomal storage disorders Special features Certain enzyme assays require additional lysosomal enzymes for their determination. Enzymes not available from other companies, are provided by Moscerdam Substrates as ready-for-use kits (e.g. for Hunter\'s and Sanfilippo D disease). All substrates are accompanied by detailed laboratory protocols, which are continuously refined through the feedback of customers. 温馨提示：不可用于临床治疗。